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CAYMAN CHEMICAL COMPANY, INC.
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CAYMAN CHEMICAL COMPANY, INC.
Catalog Number:
(75816-762)
Supplier:
Cayman Chemical Company
Description:
Simple, reproducible, and sensitive tool for measurement of glycerol in plasma and serum.
Supplier:
Cayman Chemical Company
Description:
For direct quantification of cAMP from a variety of biological samples.
Supplier:
Cayman Chemical Company
Description:
Cyclic di-AMP (sodium salt), Purity: >/=98%, A second messenger produced by bacteria, but not by mammals, Synonyms: c-di-AMP, Cyclic di-Adenosine monophosphate, 3',5'-Cyclic diadenylic acid, Cyclic diadenylate, Size: 1mg
Catalog Number:
(76543-954)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
A synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.
Catalog Number:
(76544-164)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-046)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-720)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-402)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-172)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-114)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76293-152)
Supplier:
Cayman Chemical Company
Description:
Stimulator of interferon genes (STING) is a component of the innate immune response that binds to cyclic dinucleotides, which are bacterial second messengers, leading to activation of NF-κB and transcription of immunomodulatory genes, including type I interferon (IFN). The H232 variant of STING is found at a 13.7% frequency in the 1000 Genome Project. The SNP variant R232 (Item No. 22816) is the most common variant in the human population, found at a frequency of 57.9%. Various mutations in STING either reduce or increase its activity. Gain-of-function mutations in STING, including R284M (Item No. 23594) and V155M, lead to constitutive activation and enhancement of the type I IFN response. The V155M mutation is associated with a systemic inflammatory condition, including pulmonary fibrosis and autoimmune factors. Mutations that reduce STING activity include K224R (Item No. 23593), which reduces ubiquitination of STING thereby disrupting its localization within the cell, and the double mutation G230A, R293Q (Item No. 23592), which reduces the IFN response. A T596A mutation present in the mouse strain Goldenticket leads to a complete loss of STING protein and lack of a type I IFN response to infection by Listeria.
Catalog Number:
(76544-496)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-348)
Supplier:
Cayman Chemical Company
Description:
A mixture of phytocannabinoids in an acetonitrile solution intended for HPLC-UV or LC- or GC-MS
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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