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CAYMAN CHEMICAL COMPANY, INC.
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CAYMAN CHEMICAL COMPANY, INC.
Catalog Number:
(76544-238)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
Resolvin D2 ELISA kit is a competitive assay that can be used for quantification of RvD2.
Catalog Number:
(76544-424)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-556)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-260)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-708)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-726)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.
Catalog Number:
(76544-230)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
PPM-18, Purity >/=95%, CAS 65240-86-0, MF: C17H11NO3, MW: 277.3, Synonyms: NSC 73233, N-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-benzamide, naphthoquinone compound that inhibits NF-KB activation in vitro and in vivo, Formulation: A crystalline solid, Size: 10mg
Catalog Number:
(76544-634)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(75817-102)
Supplier:
Cayman Chemical Company
Description:
Neutrophil/Monocyte Respiratory Burst Assay Kit provides PMA, dihydrorhodamine 123, and additional reagents necessary for inducing and quantifying a respiratory burst response in neutrophils and monocytes by flow cytometry. The assay can be performed on whole blood or on cells in various types of cell culture media. Because the assay reagents are not species-specific, this assay can be used in any species or cell type capable of producing a NADPH oxidase-dependent respiratory burst response.
Catalog Number:
(75816-984)
Supplier:
Cayman Chemical Company
Description:
For rapid and easy determination of GSH in whole cells.
Catalog Number:
(76544-064)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(75816-690)
Supplier:
Cayman Chemical Company
Description:
A sensitive, non-radioactive method for detecting HIF-1α from whole cell lysates.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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