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(1H-Benzoimidazol-2-yl)methanol
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(1H-Benzoimidazol-2-yl)methanol
Supplier:
TCI America
Description:
[Cross-linking Reagent]
CAS Number: 55750-62-4 MDL Number: MFCD00043141 Molecular Formula: C11H10N2O6 Molecular Weight: 266.21 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Color: White Melting point (°C): 168 Storage Temperature: 0-10°C
Supplier:
Adipogen
Description:
NVP-BEZ235 is an imidazo[4,5-c]quinoline derivative that inhibits PI3K and mTOR kinase activity by binding to the ATP-binding cleft of these enzymes. In cellular settings using human tumor cell lines, this molecule is able to effectively and specifically block the dysfunctional activation of the PI3K pathway, inducing G1 arrest at IC(50) values 3-10nM in biological cell growth and viability assays. In addition NVP-BEZ235 shows effective IC(50) values in in vitro tests against mTor and PI3K family members of 10nM.
Supplier:
Adipogen
Description:
Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.
Catalog Number:
(PI22297)
Supplier:
Invitrogen
Description:
Thermo Scientific Pierce BMPH is a short, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
Catalog Number:
(76652-012)
Supplier:
AMBEED, INC
Description:
N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide, Purity: 97%, CAS Number: 1889279-16-6, Appearance: Solid, Storage: Sealed in dry, 2-8C, Size: 25MG
Catalog Number:
(76481-696)
Supplier:
AAT BIOQUEST INC
Description:
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a non-cleavable and membrane permeable crosslinker.
Supplier:
Adipogen
Description:
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Catalog Number:
(102991-930)
Supplier:
Adipogen
Description:
SU-6668 is a potent ATP-competitive PDGFR, VEGF and FGFR inhibitor. It has a Ki of 8nM against PDGFR. It is an anti-angiogenic and anti-tumor agent that induces regression of established tumors.
Catalog Number:
(TCB2836-100MG)
Supplier:
TCI America
Description:
CAS Number: 472-15-1
Molecular Formula: C30H48O3 Molecular Weight: 456.71 Purity/Analysis Method: >97.0% (GC,T) Form: Crystal Melting point (°C): 294 Specific rotation [a]20/D: 7.8 deg (C=0.9, Pyridine)
Supplier:
TCI America
Description:
CAS Number: 4350-09-8
MDL Number: MFCD00064341 Molecular Formula: C11H12N2O3 Molecular Weight: 220.23 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Specific rotation [a]20/D: -33 deg (C=1, H2O)
Supplier:
TCI America
Description:
Abiraterone Acetate, Purity: >98.0%(HPLC)(T), Cas number: 154229-18-2, Molecular Formula: C26H33NO2, Molecular Weight: 391.56, Appearance: White - Very pale yellow Solid crystal powder, Synonyms: 3B-17-(3-Pyridyl)androsta-5,16-dien-3-ol Acetate, Size: 1G
Supplier:
BeanTown Chemical
Description:
CAS: 6363-53-7; EC No: 200-716-5; MDL No: MFCD00149343; RTECS: OO5250000
Powder; Molecular Formula: C12H22O11·H2O; MW: 360.31
Optical Rotation: [α]20/D +130±2°, c = 4% in water
Supplier:
TCI America
Description:
[Cross-linking Reagent]
CAS Number: 58626-38-3 MDL Number: MFCD00005514 Molecular Formula: C15H10N2O6 Molecular Weight: 314.25 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Color: White Melting point (°C): 181 Storage Temperature: 0-10°C
Supplier:
Adipogen
Description:
Antagonizing the Chk1-mediated cell cycle checkpoints has emerged as an attractive target for anticancer therapy. If Chk1 activity is blocked, DNA-damaged or spindle-disrupted cells would exit cell cycle arrest before full repair and subsequently undergo mitotic catastrophe or cell death. Chk1 inhibitors consequently increase the therapeutic index of DNA-damaging or antimitotic agents as well. PF-0477736 is a selective, potent ATP-competitive Chk1 inhibitor, derived from PF-0394691, inhibits Chk1 (Ki, 0.49nM) and Chk2 (Ki, 47nM) in vitro. In tests, PF-0477736 was identified as a potent, selective ATP-competitive small-molecule inhibitor that inhibits Chk1 with a Ki of 0.49nM. PF-0477736 abrogates cell cycle arrest induced by DNA damage and enhances cytotoxicity of clinically important chemotherapeutic agents, including gemcitabine and carboplatin. In xenografts, PF-0477736 enhanced the antitumor activity of gemcitabine in a dose-dependent manner. PF-0477736 combinations were well tolerated with no exacerbation of side effects commonly associated with cytotoxic agents.
Catalog Number:
(76484-664)
Supplier:
AAT BIOQUEST INC
Description:
FMOC-Lys(Biotin)-OH is a lysine derivative for the preparation of biotin-labeled peptides by FMOC-SPPS.
Supplier:
MP Biomedicals
Description:
Uridine is one of the four basic components of ribonucleic acid (RNA); the other three are adenosine, guanosine, and cytidine. Upon digestion of foods containing RNA, uridine is released from RNA and is absorbed intact in the gut. Uridine plays a role in the glycolysis pathway of galactose.
Uridine is used in treatment of bipolar disorder associated with mood swings.Uridine is used in metabolic labeling and analysis of rRNA processing.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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