4-[(PYrazin-2-ylcarbonyl)amino]butanoic+acid
Catalog Number:
(RK35035)
Supplier:
Restek
Description:
Contains: Chain, Compound (CAS#), % by Weight; C14:00 Methyl myristate (124-10-7), 0.1%; C16:00 Methyl palmitate (112-39-0), 26.3%; C16:01 Methyl palmitoleate (1120-25-8), 0.4%; C17:00 Methyl heptadecanoate (1731-92-6), 0.3%; C18:00 Methyl stearate (112-61-8), 33.7%; C18:01 Methyl oleate (112-62-9), 34.3%; C18:02 Methyl linoleate (112-63-0), 3.1%; C18:03 Methyl linolenate (301-00-8), 0.2%; C20:00 Methyl arachidate (1120-28-1), 1.3%; C20:01 Methyl eicosenoate (20839-34-3), 0.1%; C22:00 Methyl behenate (929-77-1), 0.2%
Catalog Number:
(10101-440)
Supplier:
Prosci
Description:
NEUROD6 contains 1 basic helix-loop-helix (bHLH) domain. It activates E box-dependent transcription in collaboration with TCF3/E47 and may be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. It transactivates the promoter of its own gene.NEUROD6 is a member of the NEUROD (NEUROD1; MIM 601724) family of basic helix-loop-helix (bHLH) transcription factors (Guo et al., 2002 [PubMed 12357074]).
Catalog Number:
(76548-230)
Supplier:
StatLab
Description:
Proprietary progressive nuclear stain, considered a hybrid hematoxylin product.
Supplier:
TCI America
Description:
CAS Number: 2353-45-9
MDL Number: MFCD00013053 Molecular Formula: C37H36N2O10S3 Molecular Weight: 808.84 Purity/Analysis Method: >85.0% (HPLC,E) Form: Crystal Lambda max.: 624 nm (0.02mol/L AcONH4 sol.)
Catalog Number:
(10303-676)
Supplier:
Bioss
Description:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Catalog Number:
(10301-890)
Supplier:
Bioss
Description:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Catalog Number:
(IC856126)
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Useful for stabilizing sulfhydryl-containing enzymes.
Catalog Number:
(89153-656)
Supplier:
Enzo Life Sciences
Description:
The trans-Golgi network (TGN) is part of the secretory pathway of eukaryotic cells which is distinct from the Golgi stack.The TGN is important in the later stages of protein secretion where it seems to play a key role in the sorting and targeting of secreted proteins to the correct destination. Brefeldin A (Prod. No. BML-G405) causes the contents of the Golgi stack to be redistributed into the endoplasmatic reticulum while the TGN collapse upon the microtubule organizing center. This makes immunofluorescence detection of TGN38, following Brefeldin A treatment, a useful tool for the discrimination of the TGN from the Golgi stack.
Catalog Number:
(10410-776)
Supplier:
Bioss
Description:
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
Catalog Number:
(10255-036)
Supplier:
Bioss
Description:
DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol.Human liver contains isoforms of dihydrodiol dehydrogenase (DD1, DD2, DD3 and DD4), which belong to the aldo-oxo reductase/aldo-keto reductase (AKR) superfamily, have 20Alpha- or 3Alpha-hydroxysteroid dehydrogenase (HSD) activity. DD1 is also designated AKR1C1, DDH or DDH1 while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3Alpha-HSD are alternate designations for DD3, while DD4 also can be called AKR1C4, CD or CHDR. DD1 and DD2 are 20Alpha-HSDs, whereas DD3 and DD4 are the 3Alpha-HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20Alpha-HSD catalyzes the reaction of progesterone to the inactive form 20Alpha-hydroxyprogesterone. The 3Alpha-HSD is a cytosolic, monomeric, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products. DD1 and DD2 are ubiquitously expressed, whereas DD4 mRNA is restricted to the liver.
Catalog Number:
(10410-778)
Supplier:
Bioss
Description:
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
Catalog Number:
(75928-498)
Supplier:
Rockland Immunochemical
Description:
Anti-HMW Host Cell Proteins Antibody recognizes high molecular weight protein fractions from E.coli. This antibody has been anlyzed by 2D electrophoresis western blot to assure highest possible coverage of E.coli HCP. Host Cell Proteins are process-related impurities derived from a host cell expression system that may be present in trace amounts in a final drug substance. HCP Antibodies are used to detect impurities in biologically-based therapeutics. Detecting impurities often unseen by 1-D electrophoresis, a 2D electrophoresis western blot analysis delivers more complete insight into the immunocoverage of protein components of the host cell lysate.
Catalog Number:
(76214-450)
Supplier:
Ace Glass
Description:
Benchtop purification kits designed for the Cannabis Industry.
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Catalog Number:
(76080-780)
Supplier:
Bioss
Description:
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM].
Catalog Number:
(10473-592)
Supplier:
Bioss
Description:
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Supplier:
TCI America
Description:
CAS Number: 93379-49-8
MDL Number: MFCD00010079 Molecular Formula: C31H30O4 Molecular Weight: 466.58 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Melting point (°C): 196
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