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2-(Phenoxymethyl)benzoic+acid
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2-(Phenoxymethyl)benzoic+acid
Catalog Number:
(102988-314)
Supplier:
Adipogen
Description:
Mycotoxin
Supplier:
MP Biomedicals
Description:
Arachidonic Acid is an essential fatty acid. Occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and is a constituent of animal phosphatides.
Arachidonic Acid is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic acid plays a key role in cellular regulation and is controlled through multiple interconnected pathways. Arachidonic acid (AA) is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via cytochrome p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, smooth muscle contraction, chemotaxis, cell proliferation and differentiation, and apoptosis. AA has been demonstrated to bind to the a subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane. If ethanol is undesirable, arachidonic acid may be dissolved in acetonitrile, DMF, or DMSO. Simply evaporate the ethanol under a gentle stream of nitrogen (be certain not to evaporate the material to dryness) and redissolve the arachidonic acid in the solvent of choice.Just prior to use, make dilutions of the stock solution into aqueous buffer or isotonic saline to bring the arachidonic acid to the desired concentration. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiologic effects at low concentrations. A control using the solvent in the absence of the prostaglandin will address this potential variable. We do not recommend storing the aqueous solution for more than one day. It is difficult to obtain aqueous solutions of arachidonic acid directly. However, an organic solvent free solution of arachidonic acid can be prepared using concentrated basic buffers (pH > 8.0 and ionic strength not less than 0.1 M). Add 400 μL of cold buffer (0 °C) per mg of arachidonic acid and agitate vigorously and/or ultrasonicate.
Supplier:
TCI America
Description:
CAS Number: 60-12-8
MDL Number: MFCD00002886 Molecular Formula: C8H10O Molecular Weight: 122.17 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 219 Melting point (°C): -27 Flash Point (°C): 108 Specific Gravity (20/20): 1.02
Supplier:
Adipogen
Description:
Boron-containing macrolide antibiotic
Catalog Number:
(10282-042)
Supplier:
Bioss
Description:
The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Supplier:
Thermo Scientific Chemicals
Description:
Sodium acetate buffer solution pH, 5.2 is been widely used in for precipitation of nucleic acids and preparation of gel stains for protein gel electrophoresis. Sodium acetate buffer solution is suitable for precipitation of DNA, elution of proteins and for use in molecular biology applications such as Chip-on-Chip assay and in vitro enzyme inhibition assay.
Supplier:
Adipogen
Description:
SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38alpha MAP kinase (IC(50) of 3.2nM) over p38beta MAP kinase (IC(50) of 122nM).
Supplier:
AMBEED, INC
Description:
(S)-3-(((3-Ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide, Purity: 98%, CAS Number: 779353-01-4, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 1mg
Catalog Number:
(77685-409)
Supplier:
AMBEED, INC
Description:
NG52 ≥98%
Supplier:
MP Biomedicals
Description:
Folinic acid calcium salt, pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate.
Supplier:
TCI America
Description:
CAS Number: 110-80-5
MDL Number: MFCD00002869 Molecular Formula: C4H10O2 Molecular Weight: 90.12 Purity/Analysis Method: >99.0% (GC) Form: Clear Liquid Boiling point (°C): 135 Flash Point (°C): 44 Specific Gravity (20/20): 0.93
Supplier:
Matrix Scientific
Description:
MF=C5H9N3O MW=127.15 CAS=73616-27-0 MDL=MFCD08063809 1G
Catalog Number:
(BJ32941-100ML)
Supplier:
Honeywell Research Chemicals
Description:
Methyl Red solution, Indictor Reagent, Grade: Acid-base indicator, Analytical, Cas number: 76-59-5, Molecular Formula: C15H15N3O2, Molar mass: 282.22 g/mol, Container: Glass bottle, Size: 100ml
Supplier:
Adipogen
Description:
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC(50) of 6.6nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRbeta, IGF-1R, EGFR.
Supplier:
Adipogen
Description:
CGI1746 was identified as a selective and potent ATP-competitive BTK inhibitor with an IC(50) of 1.9nM. It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.
Supplier:
Adipogen
Description:
Macrolide antibiotic
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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