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Methyl+2-(4-methylpyridin-2-yl)acetate
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Methyl+2-(4-methylpyridin-2-yl)acetate
Supplier:
AOB CHEM USA
Description:
1-Bromo-4-chloro-3-ethoxy-2-methylbenzene ≥97%
Supplier:
AOB CHEM USA
Description:
5-(2-Ethoxy-5-fluorophenyl)thiazol-2-amine ≥95%
Supplier:
AOB CHEM USA
Description:
3-Bromo-4-ethoxy-2-fluorobenzoic acid ≥97%
Supplier:
AOB CHEM USA
Description:
4-Bromo-2-ethoxy-1-(trifluoromethyl)benzene ≥97%
Supplier:
AOB CHEM USA
Description:
3-Bromo-2-ethoxy-5-(trifluoromethyl)benzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
(5-Chloro-3-ethoxy-2-fluorophenyl)trimethylsilane ≥97%
Supplier:
Adipogen
Description:
Selumetinib (AZD6244) is a second-generation, orally available, potent and selective ATP non-competitive inhibitor of MEK 1/2. In direct assays, AZD6244 selectively inhibits purified active MEK1 and MEK2 with an IC(50) of 14nM, and AZD6244 has reported IC(50) values of <lt/>100nm for MEK1 in ELISA assays and in bindings assays against recombinant domains of MEK2, Kd values were 53nM for AZD6244. AZD6244 demonstrated very effective anti-proliferation effects against several different cell lines with IC(50) values ranging from a low of 3nM to <lt/> 1µM depending upon the cell system used, and the compound inhibits basal and growth factor-stimulated phosphorylation of ERK1/ 2 with IC(50) concentrations <lt/> 40nM. AZD6244 has demonstrated potent dose-dependent antitumor activity against a panel of mouse xenograft models of colorectal, pancreatic, liver, skin, and lung cancer, and inhibition of tumor growth was found to correlate with the reduction of phospho-ERK1/2 levels in tumors.
Supplier:
AMBEED, INC
Description:
4-Chloro-2-ethoxy-5-fluoropyrimidine 95%
Supplier:
AOB CHEM USA
Description:
3-Ethoxy-4-(trifluoromethoxy)phenylboronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(6-Chloro-2-ethoxy-3-fluorophenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(3-Chloro-2-ethoxy-4-methoxyphenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(2-Ethoxy-3-(trifluoromethyl)phenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(2-Ethoxy-5-(methoxycarbonyl)phenyl)boronic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050309-500MG , MDL Number: MFCD13560710
Catalog Number:
(101925-232)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063146-500MG , MDL Number: MFCD11519737
Supplier:
AOB CHEM USA
Description:
2-(4-Ethoxy-3-isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥97%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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