Methyl+2-(4-methylpyridin-2-yl)acetate
Supplier:
AOB CHEM USA
Description:
1-Bromo-4-chloro-3-ethoxy-2-methylbenzene ≥97%
Supplier:
AOB CHEM USA
Description:
5-(2-Ethoxy-5-fluorophenyl)thiazol-2-amine ≥95%
Supplier:
AOB CHEM USA
Description:
3-Bromo-4-ethoxy-2-fluorobenzoic acid ≥97%
Supplier:
AOB CHEM USA
Description:
4-Bromo-2-ethoxy-1-(trifluoromethyl)benzene ≥97%
Supplier:
AOB CHEM USA
Description:
3-Bromo-2-ethoxy-5-(trifluoromethyl)benzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
(5-Chloro-3-ethoxy-2-fluorophenyl)trimethylsilane ≥97%
Supplier:
Adipogen
Description:
Selumetinib (AZD6244) is a second-generation, orally available, potent and selective ATP non-competitive inhibitor of MEK 1/2. In direct assays, AZD6244 selectively inhibits purified active MEK1 and MEK2 with an IC(50) of 14nM, and AZD6244 has reported IC(50) values of <lt/>100nm for MEK1 in ELISA assays and in bindings assays against recombinant domains of MEK2, Kd values were 53nM for AZD6244. AZD6244 demonstrated very effective anti-proliferation effects against several different cell lines with IC(50) values ranging from a low of 3nM to <lt/> 1µM depending upon the cell system used, and the compound inhibits basal and growth factor-stimulated phosphorylation of ERK1/ 2 with IC(50) concentrations <lt/> 40nM. AZD6244 has demonstrated potent dose-dependent antitumor activity against a panel of mouse xenograft models of colorectal, pancreatic, liver, skin, and lung cancer, and inhibition of tumor growth was found to correlate with the reduction of phospho-ERK1/2 levels in tumors.
Supplier:
AMBEED, INC
Description:
4-Chloro-2-ethoxy-5-fluoropyrimidine 95%
Supplier:
AOB CHEM USA
Description:
3-Ethoxy-4-(trifluoromethoxy)phenylboronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(6-Chloro-2-ethoxy-3-fluorophenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(3-Chloro-2-ethoxy-4-methoxyphenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(2-Ethoxy-3-(trifluoromethyl)phenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(2-Ethoxy-5-(methoxycarbonyl)phenyl)boronic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050309-500MG , MDL Number: MFCD13560710
Catalog Number:
(101925-232)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063146-500MG , MDL Number: MFCD11519737
Supplier:
AOB CHEM USA
Description:
2-(4-Ethoxy-3-isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥97%
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