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Pentafluorophenyl+isothiocyanate
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Pentafluorophenyl+isothiocyanate
Supplier:
Adipogen
Description:
The lymphocyte-specific kinase (Lck) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and natural killer (NK) cells. Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling mediated by the T cell receptor (TCR), which leads to normal T cell development and activation. Selective inhibition of Lck is expected to offer a new therapy for the treatment of T-cell-mediated autoimmune and inflammatory disease. AMG-47 is one of two optimized chemical compounds that has been shown to be extremely effective in vivo and in vitro in inhibiting Lck as well as a number of other receptor tyrosine kinases. In an anti-CD3/ IL-2 mouse model system AMG-47 has been shown to be effective in inhibiting the Lck mediated anti-inflammatory activity (ED50 11 mg/kg; 630nM) in vivo. In multiple other in vitro assays, AMG-47 exhibits subnanomolar inhibition against Lck, and low (<lt/>10nM) inhibition against other hard to inhibit kinases such as KDR and SRC and MAPK alpha (p38alpha). Moreover at slightly higher doses but well under 10µM, AMG-47 effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2µM.
Supplier:
ALADDIN SCIENTIFIC
Description:
Ethyl 5-amino-1-phenyl-4-pyrazolecarboxylate is a heterocyclic building block.Ethyl 5-amino-1-phenyl-4-pyrazolecarboxylate may be used as internal standard for the GC-MS determination of etomidate [ethyl-1-(1-phenylethyl)-1H-imidazole-5-carboxylate] in mouse brain tissue.
Supplier:
AOB CHEM USA
Description:
(4-Isobutoxy-3-(trifluoromethyl)phenyl)boronic acid ≥97%
Supplier:
AMBEED, INC
Description:
Ethyl-5-amino-1-phenyl-1H-pyrazole-4-carboxylate 98%
Supplier:
AMBEED, INC
Description:
(3-((3-Fluorobenzyl)oxy)phenyl)boronic acid, Purity: 98%, CAS number: 1072951-62-2, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100MG
Supplier:
AMBEED, INC
Description:
(2-Fluoro-5-(propylcarbamoyl)phenyl)boronic acid, Purity: 98%, CAS Number: 874289-48-2, Appearance: Solid, Storage: Sealed in dry, 2-8C, Size: 250MG
Supplier:
AOB CHEM USA
Description:
(2-Fluoro-3-(trimethylsilyl)phenyl)boronic acid ≥97%
Supplier:
AMBEED, INC
Description:
4-(4-Chlorobenzyloxy)phenylboronic acid 95%
Supplier:
AMBEED, INC
Description:
3-(Trifluoromethyl)phenylboronic acid 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042331-1G , MDL Number: MFCD01860907
Supplier:
AMBEED, INC
Description:
3-Nitro-5-(1-pyrrolidinylcarbonyl)phenylboronic acid 98%
Supplier:
AMBEED, INC
Description:
4-(Furfurylcarbamoyl)phenylboronic acid 98%
Catalog Number:
(77157-706)
Supplier:
AMBEED, INC
Description:
Phenyl Trifluoromethanesulfonate, Purity: 98%, CAS Number: 17763-67-6, Appearance: Form: liquid/Colour: Colorless - Very pale yellow, Storage: Inert atmosphere, Room Temperature, Size: 1g
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054005-500MG , MDL Number: MFCD11036961
Catalog Number:
(101810-678)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 020738-500MG , MDL Number: MFCD00514518
Supplier:
AOB CHEM USA
Description:
(3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid ≥97%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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