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Dimethylaminophenylacetonitrile+hydrochloride
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Dimethylaminophenylacetonitrile+hydrochloride
Catalog Number:
(10061-810)
Supplier:
Prosci
Description:
CARM1 Antibody: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
Supplier:
AMBEED, INC
Description:
tert-Butyl (piperidin-2-ylmethyl)carbamate, Purity: 97%, CAS Number: 141774-61-0, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 1G
Catalog Number:
(10750-384)
Supplier:
Prosci
Description:
EBI3 Antibody: EBI3 is a subunit in two distinct heterodimeric cytokines: interleukin-27 (IL-27) and IL-35. Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 (also known as TCCR) and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet. IL-35 is composed of EBI3 and the p35 subunit of IL-12 and has been reported to have therapeutic effects against collagen-induced arthritis by expanding the population of regulatory T cells and suppressing Th17 cells. At least two isoform of EBI3 are known to exist.
Supplier:
AMBEED, INC
Description:
Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate, Purity: 98+%, CAS Number: 1364488-67-4, Appearance: Off-white Solid, Storage: Inert atmosphere, 2-8 C, Size: 10mg
Supplier:
TCI America
Description:
CAS Number: 99724-19-3
MDL Number: MFCD00059040 Molecular Formula: C9H18N2O2 Molecular Weight: 186.26 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 54
Supplier:
Enzo Life Sciences
Description:
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
Catalog Number:
(103280-260)
Supplier:
Novus Biologicals
Description:
The gamma Sarcoglycan Antibody from Novus Biologicals is a rabbit polyclonal antibody to gamma Sarcoglycan. This antibody reacts with human. The gamma Sarcoglycan Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(10075-662)
Supplier:
Prosci
Description:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of 4 distinct subunits (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is also potentiated by phosphorylation at Ser845. In addition, phosphorylation of this site has been linked to synaptic plasticity as well and learning and memory.
Supplier:
Ricca Chemical
Description:
Xylenol orange indicator 0.1 % (w/v) in aqueous solution
Supplier:
TCI America
Description:
CAS Number: 793-24-8
Molecular Formula: C18H24N2 Molecular Weight: 268.40 Purity/Analysis Method: >98.0% (GC) Form: Pellet Boiling point (°C): 165 Melting point (°C): 51 Flash Point (°C): 204
Supplier:
AMBEED, INC
Description:
5-Bromo-o-toluidine 97%
Supplier:
Adipogen
Description:
CP-724714 is an oral, selective and potent ErbB-2 (HER2) kinase inhibitor with an IC(50) of 10 nM. It has <gt/>640-fold selectivity for ErbB-2 (HER2) over EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met.
Catalog Number:
(10429-284)
Supplier:
Bioss
Description:
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
Catalog Number:
(TCC1876-25G)
Supplier:
TCI America
Description:
CAS Number: 95-79-4
MDL Number: MFCD00007779 Molecular Formula: C7H8ClN Molecular Weight: 141.60 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 237 Flash Point (°C): 160 Freezing point (°C): 23
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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