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(Bromomethyl)cyclobutane
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(Bromomethyl)cyclobutane
Supplier:
AMBEED, INC
Description:
2,4,6-Tris(bromomethyl)mesitylene 95%
Catalog Number:
(76924-282)
Supplier:
AOB CHEM USA
Description:
4-(Bromomethyl)phenylboronic acid ≥97%
Supplier:
AMBEED, INC
Description:
2-(Bromomethyl)-6-fluoropyridine, Purity: 95%, CAS Number: 100202-78-6, Appearance: Colorless to Pale-yellow to Yellow-brown Liquid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:
Matrix Scientific
Description:
MF=C9H9BRO2 MW=229.08 CAS=2417-73-4 MDL=MFCD03425900 25G
Catalog Number:
(76100-036)
Supplier:
Bioss
Description:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Catalog Number:
(TCB5008-200MG)
Supplier:
TCI America
Description:
4-(Bromomethyl)-7-(diethylamino)coumarin, Purity: >98.0%(T), CAS Number: 1256259-14-9, Molecular Formula: C14H16BrNO2, Molecular Weight: 310.19, Size: 200MG
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042587-5G , MDL Number: MFCD00225209
Supplier:
AMBEED, INC
Description:
4-tert-Butyl-1-(bromomethyl)benzene 98%
Supplier:
AMBEED, INC
Description:
3-Bromomethyl-4-fluorobenzeneboronic acid pinacol ester 97%
Catalog Number:
(102842-280)
Supplier:
Matrix Scientific
Description:
[1-(Bromomethyl)cyclopropyl]acetonitrile ≥95%
Supplier:
AMBEED, INC
Description:
4-Bromomethyl-1,2-dihydroquinoline-2-one 97%
Supplier:
AMBEED, INC
Description:
4-Bromomethyl-3-fluorobenzeneboronic acid pinacol ester 95%
Catalog Number:
(101912-954)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057307-1G , MDL Number: MFCD03425263
Supplier:
AMBEED, INC
Description:
tert-Butyl 3-(bromomethyl)-1H-indole-1-carboxylate, Purity: 95%, CAS Number: 96551-21-2, Appearance: Light-red to Brown Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Catalog Number:
(102842-140)
Supplier:
Matrix Scientific
Description:
1,3-Bis(bromomethyl)-2-fluorobenzene ≥97%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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