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(Bromomethyl)cyclobutane


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Supplier:  TCI America
Description:   CAS Number: 35335-16-1
MDL Number: MFCD03411745
Molecular Formula: C8H6Br4
Molecular Weight: 421.75
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 160
MSDS SDS
Supplier:  TCI America
Description:   CAS Number: 20248-86-6
MDL Number: MFCD00094419
Molecular Formula: C14H12Br2
Molecular Weight: 340.06
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Melting point (°C): 171
MSDS SDS
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 007522-1G , MDL Number: MFCD03452790

Supplier:  AMBEED, INC
Description:   1-Bromo-3-(bromomethyl)-5-(trifluoromethyl)benzene, Purity: 95%, CAS Number: 954123-46-7, Appearance: Colorless to Yellow Liquid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Supplier:  APOLLO SCIENTIFIC
Description:   4-Methoxybenzyl bromide, Technical Grade
Supplier:  Matrix Scientific
Description:   MF=C33H25BRN4 MW=557.50 CAS=124750-51-2 MDL=MFCD00665221 5G
Supplier:  Matrix Scientific
Description:   MF=C9H8BR2O2 MW=307.98 CAS=78471-43-9 MDL=MFCD04114319 5G
Supplier:  AMBEED, INC
Description:   2-(Bromomethyl)-2-(2-chloro-4-(4-chlorophenoxy)phenyl)-4-methyl-1,3-dioxolane, Purity: 97%, CAS Number: 873012-43-2, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Supplier:  APOLLO SCIENTIFIC
Description:   2-Cyano-5-fluorobenzyl bromide
Catalog Number: (102842-118)

Supplier:  Matrix Scientific
Description:   3-Phenoxybenzyl bromide ≥97%
Supplier:  TCI America
Description:   CAS Number: 7703-74-4
MDL Number: MFCD00191795
Molecular Formula: C7H7Br2N
Molecular Weight: 264.95
Purity/Analysis Method: >99.0% (GC,T)
Form: Crystal
Melting point (°C): 87
MSDS SDS
Supplier:  Bioss
Description:   Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.

Supplier:  AMBEED, INC
Description:   2-(Bromomethyl)-1-chloro-3-(trifluoromethyl)benzene, Purity: 95%, CAS Number: 886500-26-1, Appearance: Colorless to light-yellow liquid, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:  AMBEED, INC
Description:   2-Fluoro-6-(trifluoromethyl)benzyl bromide 98%
Supplier:  AMBEED, INC
Description:   3-Chloro-4-methoxybenzyl bromide 95%
Catalog Number: (77265-586)

Supplier:  AMBEED, INC
Description:   2-(Bromomethyl)-1-fluoro-4-nitrobenzene, Purity: 98%, CAS Number: 454-15-9, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1g
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