(E)-3-(4-Propoxyphenyl)acrylic+acid
Supplier:
TCI America
Description:
CAS Number: 4046-02-0
MDL Number: MFCD00009190 Molecular Formula: C12H14O4 Molecular Weight: 222.24 Purity/Analysis Method: >97.0% (GC) Form: Crystal Boiling point (°C): 185 Melting point (°C): 57
Supplier:
CUBE BIOTECH
Description:
AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-55 - are highly-alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-55 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general, lighter AASTYs, like 6-55 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.
The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs. Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
Supplier:
CUBE BIOTECH
Description:
AASTYs (Acrylic acid-co-styrenes) - like AASTY 11-55 - are highly alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 11-55 is named from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-55 show higher thermodynamic stability.
The exact composition of AASTY copolymers shows different extraction efficiencies, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs. Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
Supplier:
AMBEED, INC
Description:
trans-3,4-Difluorocinnamic acid 97%
Supplier:
Bel-Art Products
Description:
Designed for use in all magnetic separation experiments, these powerful racks sequester magnetic beads so that affinity ligands (antibodies, streptavidin, or proprietary reagents for coupling nucleic acids) or rinse solutions can be added or decanted in assays.
Catalog Number:
(TCD4161-1G)
Supplier:
TCI America
Description:
CAS Number: 112897-97-9
MDL Number: MFCD00010320 Molecular Formula: C9H6F2O2 Molecular Weight: 184.14 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 196
Catalog Number:
(10001-838)
Supplier:
G-Biosciences
Description:
In high quality acrylic with platinum electrodes, the Wet/Tank Blotting System provides high quality and rapid blotting (electro-transfer) of mini handcast and precast gels
Supplier:
TCI America
Description:
CAS Number: 830-09-1
MDL Number: MFCD00004398 Molecular Formula: C10H10O3 Molecular Weight: 178.19 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 190
Catalog Number:
(77392-564)
Supplier:
CUBE BIOTECH
Description:
Each membrane protein has its native lipid environment. Therefore, each lipid environment is unique to each membrane protein. Moreover, it is this lipid environment that synthetic polymers like AASTYs interact with. Therefore, one needs a broader selection of polymers since there is not one AASTY that fits each phospholipid composition. To address this question, AASTYs come in three different ratios of acrylic acid to styrene. The ratios differ in hydrophilic property of AASTY, which results in different affinities to varying membrane lipid compositions. The second feature to screen for when it comes to AASTY is the size of the resulting nanodiscs. One of AASTY's most excellent features, compared to SMA or DIBMA, is that its nanodiscs are pretty uniform in size. Therefore, the correct fitting nanodisc size must be determined before.
Supplier:
Spectrum Chemicals
Description:
N,N-Dimethylformamide, Reagent, ACS, is an organic compound that is a colorless, odorless, water miscible liquid and is commonly used in chemical reactions as a solvent. It's an aprotic solvent that has a high boiling point. It is used in the fabrication of plastics and acrylic fibers as well as being used in peptide coupling as a solvent. As an ACS grade Reagent, Spectrum Chemical manufactured compound is used as the quality standard against which other substances are grade and has met the toughest regulatory standards for quality and pureness
Supplier:
TCI America
Description:
CAS Number: 31098-21-2
MDL Number: MFCD00010139 Molecular Formula: C7H12O5S Molecular Weight: 246.32 Purity/Analysis Method: >97.0% (HPLC,T) Form: Crystal Melting point (°C): 295
Catalog Number:
(103792-886)
Supplier:
ADVANCED BIOMATRIX, INC. MS
Description:
Ruthenium Visible Light Photoinitiator (400-450nm)
Supplier:
Spectrum Chemicals
Description:
L-Asparagine, Monohydrate, FCC - The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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Catalog Number:
(82024-547)
Supplier:
VWR International
Description:
Strong, crystal-clear acrylic dispenser makes film supply visible and features a serrated cutting blade.
Supplier:
VWR International
Description:
Dispensers are constructed of tough, clear acrylic to provide visibility of glove size and material.
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