1-Bromo-3-(methoxymethyl)benzene
Catalog Number:
(76483-514)
Supplier:
AAT BIOQUEST INC
Description:
DiI, DiO, DiD and DiR dyes are a family of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures.
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Supplier:
AMBEED, INC
Description:
6-ECDCA ≥98%
Supplier:
Adipogen
Description:
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.
Supplier:
AMBEED, INC
Description:
4-Aminonicotinaldehyde, Purity: 98%, CAS Number: 42373-30-8, Appearance: Form: solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 1g
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00006317
Beilstein Registry No.: 109868
Catalog Number:
(101848-112)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039750-5G , MDL Number: MFCD00137840
Supplier:
AMBEED, INC
Description:
3-Amino-2-(trifluoromethyl)pyridine 97%
Supplier:
Matrix Scientific
Description:
MF=C5H6N2O MW=110.12 Cas=38767-72-5 1G
Supplier:
TCI America
Description:
Roxithromycin, Purity: >95.0%(HPLC), Cas number: 80214-83-1, Molecular Formula: C41H76N2O15, Molecular Weight: 837.06, Synonyms: Erythromycin 9-[O-(2-Methoxyethoxy)methyloxime], Appearance: White - Almost white solid crystal powder, Size: 25G
Catalog Number:
(101840-106)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 035807-500MG , MDL Number: MFCD02938037
Supplier:
Thermo Scientific Chemicals
Description:
Roxithromycin is used to block bacterial protein synthesis
Catalog Number:
(TCL0216-5G)
Supplier:
TCI America
Description:
CAS Number: 98079-52-8
MDL Number: MFCD00214312 Molecular Formula: C17H19F2N3O3 Molecular Weight: 387.81 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal
Supplier:
AMBEED, INC
Description:
2-Morpholinoacetic acid hydrochloride, Purity: 97%, CAS Number: 89531-58-8, Appearance: Form: Crystal - Powder / Colour: White - Very pale yellow, Storage: Inert atmosphere, Room Temperature, Size: 1G
Catalog Number:
(102988-736)
Supplier:
Adipogen
Description:
Cell permeable compound capable of slowing anaphase-promoting complex/cyclosome (APC/C)-dependent proteolysis. Inhibitor of the ubiquitin ligase activity of the APC/C by inhibiting substrate binding to Cdc20. Distinct mechanism of action than proTAME. Blocks mitotic exit only modestly when used alone in cultured cells. A strong synergistic effect is observed when Apcin and proTAME are used simultaneously, providing a more robust mitotic arrest. This may be very beneficial when treating cells that do not efficiently convert proTAME to its active parent compound (TAME) or if experiments demand strong APC/C inhibition.
Catalog Number:
(80503-392)
Supplier:
MilliporeSigma
Description:
Simvastatin, a lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation.
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