1,2-Bis(dimethylsilyl)benzene
Catalog Number:
(76694-956)
Supplier:
AMBEED, INC
Description:
Benzeneseleninic anhydride 98%
Supplier:
Adipogen
Description:
Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. In the event of problems, waste products produced by dying cells or overgrowth of contaminants will cause a change in pH, leading to a change in indicator color. For example, a culture of relatively slowly dividing mammalian cells can be quickly overgrown by bacterial contamination. This usually results in an acidification of the medium, turning it yellow. The waste products produced by the mammalian cells themselves will slowly decrease the pH, gradually turning the solution orange and then yellow. This color change is an indication that even in the absence of contamination, the medium needs to be replaced. Shown to be a weak estrogen mimic (possible through inpurities), which can enhance the growth of cells that express the estrogen receptor in cell cultures. Might be useful as a differentiation factor.
Catalog Number:
(89139-162)
Supplier:
Biotium
Description:
BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.
Catalog Number:
(76180-674)
Supplier:
MP Biomedicals
Description:
Phenol red is an acid-base indicator. It is made by condensing two moles of phenol with one mole of o-sulfobenzoic acid anhydride.
Phenol Red is used as a pH indicator in cell culture applications. A solution of phenol red will have a yellow color at a pH of 6.4 or below and a red color at a pH of 8.2 and above. Phenol red in tissue culture media can act as a weak estrogen, especially with human breast cancer cells. Phenol red can be used to measure hydrogen peroxide in cultured macrophages in multiwell plates. Store at Room Temperature (15-30 °C)
Supplier:
Adipogen
Description:
Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.
Supplier:
TCI America
Description:
CAS Number: 3383-21-9
MDL Number: MFCD00001647 Molecular Formula: C14H20O2 Molecular Weight: 220.31 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 115
Supplier:
TCI America
Description:
CAS Number: 111-21-7
MDL Number: MFCD00026213 Molecular Formula: C10H18O6 Molecular Weight: 234.25 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 300 Flash Point (°C): 174 Specific Gravity (20/20): 1.12
Supplier:
AMBEED, INC
Description:
N,N,N',N',N''-Pentamethyldiethylenetriamine 98%
Supplier:
Spectrum Chemicals
Description:
Butylated Hydroxytoluene, Granular, NF is used for its antioxidant properties in pharmaceutical gels, creams, liquids, gelatin capsules and tablets. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(76481-004)
Supplier:
AAT BIOQUEST INC
Description:
dBBr is one of the most popular thiol-reactive fluorescent tags, and is widely used to detect various thiol-containing biomolecules such as glutathione in cells.
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Supplier:
Spectrum Chemicals
Description:
BHT, Granular, FCC is used in small quantities as a food additive as an antioxidant. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Adipogen
Description:
Anti-cancer compound. Interferes with multiple cell signaling pathways, including cell cycle (cyclin D1 and cyclin E), apoptosis (activation of caspases and down-regulation of anti-apoptotic gene products), proliferation (HER-2, EGFR and AP-1), survival (PI3K/AKT pathway), invasion (MMP-9 and adhesion molecules), angiogenesis (VEGF), metastasis (CXCR-4) and inflammation (NF-kappaB, TNF, IL-6, IL-1, COX-2 and 5-LOX). Anti-angiogenic. Anti-metastatic. Anti-invasive. Chemopreventive. Sonic hedgehog (Shh) signaling pathway modulator. Downregulates Shh and Gli1. Antioxidant. Anti-inflammatory. Potent inhibitor of NF-kappaB, cyclooxygenase-2 (COX-2), lipooxygenase (LOX), and inducible nitric oxide synthase (iNOS; NOSII). Downregulates the expression of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12 and chemokines. Potent immunomodulator. Modulates several key transcription factors. Down-regulate transcription factors NF-kappaB, AP-1 and Egr-1. Down-regulates the expression of COX-2, LOX, NOS, MMP-9, uPA, TNF, chemokines, cell surface adhesion molecules and cyclin D1. Down-regulate growth factor receptors (such as EGFR and HER2) and inhibits the activity of c-Jun N-terminal kinase, protein tyrosine kinases and protein serine/threonine kinases. Neuroprotective. Anti-amyloid activity. Cardioprotective. p300/CBP-HAT inhibitor. Regulates lipid metabolism and downregulates obesity. Activates peroxisome proliferator-activated receptor-gamma (PPARgamma) and Nrf2 cell-signaling pathways. Antiviral, antibacterial, antifungal. Epigenetic agent. Interacts with histone deacetylases (HDACs), histone acetyltransferases (HATs), DNA methyltransferase I and microRNAs. Inducer of autophagy in lung adenocarcinoma cells.
Supplier:
TCI America
Description:
CAS Number: 1709-70-2
MDL Number: MFCD00026284
Molecular Formula: C54H78O3
Molecular Weight: 775.22
Purity/Analysis Method: <gt/>95.0% (GC)
Form: Crystal
Color: White
Melting point (°C): 243
Supplier:
Strem Chemicals Inc
Description:
NHC
Catalog Number:
(IC856126)
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Useful for stabilizing sulfhydryl-containing enzymes.
Supplier:
AMBEED, INC
Description:
4,4',4''-((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(2,6-di-tert-butylphenol), Purity: 97%, CAS number: 1709-70-2, Appearance: Form: Crystal - Powder / Colour: White - Almost white, Storage: Sealed in dry, Room Temperature, Size: 25G
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