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SynaptoGreen\\u2122+C18+(Equivalent+to+FM®3-25)
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SynaptoGreen\\u2122+C18+(Equivalent+to+FM®3-25)
Supplier:
AMBEED, INC
Description:
3,5-Difluorobenzene-1,2-diamine, Purity: 98%, CAS Number: 2369-29-1, Appearance: Solid or Semi-Solid or Liquid or Lump, Storage: Keep in dark place, Inert atmosphere, 2-8 deg C, Size: 5g
Catalog Number:
(10073-162)
Supplier:
Prosci
Description:
4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13 kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24 kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Catalog Number:
(10800-170)
Supplier:
Rockland Immunochemical
Description:
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) is a basic leucine-zipper (bZip) transcription factor, which regulates amino acid metabolism, DNA damage repair, chromatin remodeling, and apoptosis in response to cellular and ER stress. ATF4 works with various proteins, such as C/EBP homology protein (CHOP), aspargine synthetase (ASNS), and cAMP response element (CRE) among others to mediate cellular stress. ATF4 also regulates glucose homeostasis by suppressing beta-cell proliferation and insulin production. Furthermore, ATF4 targets the histone demethylase JMJD3 to alter chromatin structure and enhance gene transcription in response to amino acid deprivation. Anti-ATF4 is ideal for researchers interested in Cell Signaling, Oncology, Cell Differentiation, and Apoptosis; relevant pathways include MAPK signaling pathways, Activation of cAMP-Dependent PKA, CREB pathways, GPCR pathways and Rho Family GTPases.
Supplier:
AMBEED, INC
Description:
2,3-Difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, Purity: 98%, CAS Number: 1220219-43-1, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 250mg
Catalog Number:
(77622-918)
Supplier:
AMBEED, INC
Description:
tert-Butyl 3,3-difluoro-2-(hydroxymethyl)azetidine-1-carboxylate ≥98%
Supplier:
AMBEED, INC
Description:
((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate 98%
Catalog Number:
(76825-256)
Supplier:
AMBEED, INC
Description:
1,4-Difluoro-2-(prop-2-yn-1-yloxy)benzene, Purity: 97%, CAS Number: 457628-36-3, Appearance: White or colorless to yellow powder or crystals or liquid, Storage: Inert atmosphere, Room Temperature, Size: 5G
Catalog Number:
(101777-876)
Catalog Number:
(77268-374)
Supplier:
AMBEED, INC
Description:
5,6-Difluoro-1H-benzo[d]imidazole-2(3H)-thione, Purity: 97%, CAS Number: 123470-47-3, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 250mg
Catalog Number:
(89139-510)
Supplier:
Biotium
Description:
The principle of DPA/Tb3 for vesicle fusion assay is based on the fact that contact of the chelator dipicolinic acid (DPA) with terbium (III) forms an instant Tb3 -DPA complex that is ~10,000 times more fluorescent than free Tb3 . In the assay, separate vesicle populations are loaded with 2.5 mM TbCl3 in 50 mM sodium citrate, or 50 mM DPA in 20 mM NaCl.
Supplier:
AMBEED, INC
Description:
Hydrogen 3-(2-carboxylatoethyl)-5,5-difluoro-7-(1H-pyrrol-2-yl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide ≥98%
Catalog Number:
(101781-912)
Supplier:
Matrix Scientific
Description:
MF=C14H17F2No4 MW=301.29 Cas=198474-90-7 MDL=MFCD00672518 1G
Catalog Number:
(10111-590)
Supplier:
Prosci
Description:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.
Catalog Number:
(77619-476)
Supplier:
AMBEED, INC
Description:
(R)-tert-Butyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate ≥98%
Catalog Number:
(101833-858)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 032494-500MG , MDL Number: MFCD11226525
Supplier:
AMBEED, INC
Description:
3,3''-Difluoro-5'-(3-fluoro-4-formylphenyl)-[1,1':3',1''-terphenyl]-4,4''-dicarbaldehyde, Purity: 98%, CAS Number: 2088007-04-7, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1G
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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