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\\u03B1-Bromo-4-(trifluoromethoxy)toluene
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\\u03B1-Bromo-4-(trifluoromethoxy)toluene
Supplier:
ACROBIOSYSTEMS INC MS
Description:
FITC-Labeled Human FAP Protein, Fc Tag, ACROBiosystems
Supplier:
Adipogen
Description:
Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase.
Supplier:
Adipogen
Description:
Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
Catalog Number:
(89289-962)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to ANKRD26
Catalog Number:
(89148-136)
Supplier:
Enzo Life Sciences
Description:
Protective agent for SH groups
Supplier:
Adipogen
Description:
GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).
Supplier:
Adipogen
Description:
Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Blocks class I, class II and class III PI3Ks, including some downstream targets. Blocks class I PI3K persistently and class III PI3K transiently. Induces autophagy under nutrient-rich conditions and inhibits starvation-induced autophagy due to differential effects on class I versus class III PI3 kinase. Shows some limited Vps34 preference in vitro compared to PtdIns3Kgamma. However, it is typically employed in cellular studies at a concentration of 10 mM, which can inhibit all PtdIns3Ks. Can target other kinases and affect other cellular processes, such as glycogen metabolism, lysosomal acidification, endocytosis and mitochondrial permeability transition. Anticancer compound. Neuroprotective. PKA-activation dependent lipolytic agent. Enhances ATGL-dependent hydrolysis of triacylglycerols.
Catalog Number:
(94020-886)
Supplier:
National Marker
Description:
Great for jobs requiring numbering only
Catalog Number:
(89269-708)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to SLC26A9 (Middle)
Catalog Number:
(77975-561)
Supplier:
LGC STANDARDS
Description:
Aniline Point, Jet Aviation Fuel (nominal value: 58.48°C), Paragon Scientific, LGC Standards
Supplier:
Adipogen
Description:
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Supplier:
Adipogen
Description:
BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Supplier:
Adipogen
Description:
IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
Catalog Number:
(10449-212)
Supplier:
Bioss
Description:
FOLH1B
Supplier:
Adipogen
Description:
PIK-75 is a PI3K inhibitor displaying selectivity for the p110alpha isoform (IC(50) of 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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