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2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
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2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
Supplier:
Adipogen
Description:
BMS-540215 is an ATP-competitive inhibitor of human VEGFR-2, with an IC(50) of 25nM and Ki of 26nM. BMS-540215 also showed good selectivity for FGFR-1 (IC(50) of 48nM), FGFR-2 (IC(50) of 125nM), and FGFR-3 (IC(50) of 68nM).
Catalog Number:
(MFLX06447-24)
Supplier:
VWR International
Description:
Longest life of all Tygon® formulations.
Catalog Number:
(MFLX06424-24)
Supplier:
VWR International
Description:
Combines biocompatibility of silicone with chemical resistance similar to Tygon®.
Supplier:
VWR International
Description:
Durable boiling flasks have good temperature and chemical resistance.
Supplier:
MP Biomedicals
Description:
Acrylamide is a monomer used in a variety of synthetic processes to form polymers and copolymers. It polymerizes in the presence of free radicals in aqueous solutions. It is usually used to prepare polyacrylamide gels for electrophoresis separation of biomolecules.
Catalog Number:
(76051-946)
Supplier:
VWR International
Description:
Made of corrosion resistant stainless steel.
Supplier:
VWR International
Description:
No tools needed for assembly.
Supplier:
MP Biomedicals
Description:
Anhydrous Calcium Chloride is highly hygroscopic and is often used as a desiccant. Calcium plays important roles in many biological processes, including signal transduction, muscle contraction, maintenance of cell membranes and cell wall stability.
Catalog Number:
(10036-024)
Supplier:
VWR International
Description:
The Pocket Mop is a flat head mop that can be used for controlled environments.
Catalog Number:
(MFLX96403-24)
Supplier:
VWR International
Description:
Excellent biocompatibility that meets multiple classifications.
Supplier:
Adipogen
Description:
Key metabolite of the ketolytic pathway generating acetyl-CoA. Stereoselective product of D-3-hydroxybutyrate dehydreogenase. Clinically and physiologically significant stereoisomer. Energy carrier from adipocytes to peripheral tissues during fasting or exercise. Endogenous inhibitor of histone deacetylases (HDACs) 1, 3 and 4. Ligand of free fatty acid receptor 3 (FFAR3; GPR41) and hydroxycarboxylic acid receptor 2 (HCAR2; GPR109B). NLRP3 inflammasome inhibitor. Prevents K+-efflux and reduces ASC oligomerization and speck formation.
Catalog Number:
(100503-430)
Supplier:
Electron Microscopy Sciences
Description:
DGD is a removable embedding medium (for thin and thick sections) that provides embedment free sections
Supplier:
MP Biomedicals
Description:
Storage: Room Temperature
2-Mercaptoethanol is a hybrid of ethylene glycol and 1,2-ethanedithiol. It is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its diminished vapor pressure, its odour, while unpleasant, is less objectionable than related thiols. 2-Mercaptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis (typically used in SDS-PAGE sample buffer at 5% concentration). Also it reduces excess oxidative polymerization of catalysts. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure. In solution, 2-mercaptoethanol is readily oxidized in air to a disulfide, especially at alkaline pH. Because of this property, it is widely used to protect proteins, enzymes in particular, from becoming inactive. An excess of 2-mercaptoethanol (generally used at 0.01 M) will maintain the protein thiol groups in their reduced state.
Catalog Number:
(MFLX06427-24)
Supplier:
VWR International
Description:
Combines biocompatibility of silicone with chemical resistance similar to Tygon®.
Catalog Number:
(MFLX96412-24)
Supplier:
Adipogen
Description:
IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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