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1-(4-Chloro-2,3-difluorophenyl)ethanol
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1-(4-Chloro-2,3-difluorophenyl)ethanol
Catalog Number:
(102991-930)
Supplier:
Adipogen
Description:
SU-6668 is a potent ATP-competitive PDGFR, VEGF and FGFR inhibitor. It has a Ki of 8nM against PDGFR. It is an anti-angiogenic and anti-tumor agent that induces regression of established tumors.
Supplier:
Adipogen
Description:
Vorinostat (SAHA, MK0683, Zolinza) inhibits the enzymatic activity of histone deacetylases HDAC1, HDAC2 and HDAC3 (Class I) and HDAC6 (Class II) at nanomolar concentrations (IC50<lt/> 86 nM). These enzymes catalyze the removal of acetyl groups from the lysine residues of histones proteins. In some cancer cells, there is an overexpression of HDACs, or an aberrant recruitment of HDACs to oncogenic transcription factors causing hypoacetylation of core nucleosomal histones. By inhibiting histone deacetylase, vorinostat causes the accumulation of acetylated histones and induces cell cycle arrest and/or apoptosis of some transformed cells. The mechanism of the antineoplastic effect of vorinostat has not been fully characterized.
Supplier:
G-Biosciences
Description:
Glutathione Resin is designed for the affinity purification of proteins with a glutathione S-transferase (GST) tag. The resin consists of reduced glutathione (GSH) covalently coupled to 6% cross-linked agarose, via a 10-carbon spacer arm. The resin has a binding capacity of >40mg GST/ml resin.
Supplier:
TCI America
Description:
CAS Number: 23364-44-5
MDL Number: MFCD00074959 Molecular Formula: C14H15NO Molecular Weight: 213.28 Purity/Analysis Method: >99.0% (GC,T) Form: Crystal Melting point (°C): 144 Specific rotation [a]20/D: 7 deg (C=0.6, EtOH)
Supplier:
BeanTown Chemical
Description:
CAS: 75-80-9; EC No: 200-903-1; MDL No: MFCD00004671; RTECS: KM3675000
Solid; Linear Formula: Br3CCH2OH; Molecular Formula: C2H3Br3O; MW: 282.76
Melting Point: 73-79°; Boiling Point: 92-93°/10 mmHg
Light Sensitive
Supplier:
Rigaku Reagents
Description:
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Supplier:
Adipogen
Description:
Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding DHCR7 lead to increased levels of 7-DHC and the neurodevelopmental syndrome Smith-Lemli-Opitz syndrome (SLOS). 7-DHC is used as a biomarker for SLOS screenings. Inhibits human fibroblast sphingomyelinase. Shown to have cytotoxic effects on melanoma cells. In skin, photolysis of 7-DHC by ultraviolet light produces vitamin D3. UV/Vis: lambdamax 271, 282, 293nm.
Catalog Number:
(76514-244)
Supplier:
VWR International
Description:
These VWR® Plus glass door laboratory refrigerators offer versatile cold storage solutions with superior temperature control.
Catalog Number:
(IC15058980)
Supplier:
MP Biomedicals
Description:
Cesium chloride is used for the preparation of electrically conducting glasses. It is also used to make solutions for the separation of RNA from DNA by density gradient centrifugation.
Catalog Number:
(IC15376525)
Supplier:
MP Biomedicals
Description:
Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. This product exhibits metal binding properties. Hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy. Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics). Very slightly soluble in cold water (0.0016 mg/mL at 25 °C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides and carbonates. Soluble in hot dilute HCl and H2SO4.
Catalog Number:
(80058-450)
Supplier:
MilliporeSigma
Description:
An antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50=200nM, 30µM and 30µM for 5-LOX, 12-LOX and 15-LOX, respectively) over cyclooxygenase (IC50=100µM)
Catalog Number:
(101411-010)
Supplier:
Electron Microscopy Sciences
Description:
Alcoholic stain solutions are available with Congo Red 0.2%, Hematoxylin 1% in 95% alcohol, Iodine 0.5% in 95% alcohol, Iodine 0.5% in 85% alcohol, Iodine 2% in 85% alcohol, Saffron 6%, Thionin 0.5% in 20% alcohol, Aldehyde Fuchsin and Alum Hematoxylin.
Supplier:
Adipogen
Description:
TG-46 is an inhibitor of JAK2, FLT3, RET, JAK3 with IC(50) values of 6nM, 25nM, 17nM, 169nM respectively.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Alcohol, anhydrous, reagent made from specially denatured alcohol 3A.
Supplier:
Adipogen
Description:
Mubritinib is a potent, irreversible human epithelial growth factor receptor 2 (ErbB2/HER2) inhibitor (IC(50) of 6nM) which displays <gt/> 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src kinases.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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