5-(Aminosulfonyl)-2,3-dimethoxybenzoic acid
Supplier:
AOB CHEM USA
Description:
2-(3-Bromo-2-fluoro-6-iodophenyl)propan-2-ol ≥97%
Catalog Number:
(101846-118)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038741-500MG , MDL Number: MFCD12027428
Supplier:
Matrix Scientific
Description:
MF=C6H6Bio2 MW=247.83 Cas=5122-99-6 MDL=MFCD01319014 1G
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Supplier:
AMBEED, INC
Description:
(S)-N-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide, Purity: 98+%, CAS Number: 923032-37-5, Appearance: Pale-yellow to Yellow-brown Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 50mg
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4'-Iodoacetanilide 97%
Catalog Number:
(101787-866)
Supplier:
Matrix Scientific
Description:
MF=C7H7Is MW=250.10 Cas=33775-94-9 MDL=MFCD00051611 25G
Supplier:
APOLLO SCIENTIFIC
Description:
3-Iodobenzyl alcohol, Technical Grade
Supplier:
AOB CHEM USA
Description:
1,3-Difluoro-4-iodo-2-methylsulfanylbenzene ≥97%
Supplier:
Matrix Scientific
Description:
MF=C11H15I MW=274.15 Cas=85017-60-3 MDL=MFCD00079767 1G
Catalog Number:
(77692-887)
Supplier:
LGC STANDARDS
Description:
(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]propanoic Acid (3,3',5'-Triiodo-L-Thyronine), Mikromol, LGC Standards
Supplier:
AOB CHEM USA
Description:
2-Bromo-6-iodoanisole ≥95%
Supplier:
AMBEED, INC
Description:
4-Iodobenzylamine hydrochloride 97%
Supplier:
AMBEED, INC
Description:
AS-703026 98%, Ambeed.Inc
Supplier:
AMBEED, INC
Description:
2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide, Purity: 98%, CAS Number: 212631-79-3, Appearance: Form: Crystal - Powder / Colour: White - Very pale yellow, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20C, Size: 1MG
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