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1-(Hydroxymethyl)-1H-pyrazole-3-carboxylic+acid
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1-(Hydroxymethyl)-1H-pyrazole-3-carboxylic+acid
Supplier:
Enzo Life Sciences
Description:
Bcl-2 ligand.
Supplier:
BeanTown Chemical
Description:
CAS: 1617-90-9; EC No: 216-576-3; MDL No: MFCD00078054; RTECS: YY8575000
Crystalline/Powder; Molecular Formula: C21H26N2O3; MW: 354.44
Melting Point: 232° (decomposes)
Optical Rotation: [α]23/D +42.8°, c = 1 in pyridine
Supplier:
Thermo Scientific Chemicals
Description:
Specific calcium-calmodulin-dependent phosphodiesterase inhibitor
Catalog Number:
(77626-340)
Supplier:
AMBEED, INC
Description:
Dicloxacillin sodium salt monohydrate ≥98%
Supplier:
TCI America
Description:
Solifenacin Succinate, Purity: >98.0%(HPLC), Cas number: 242478-38-2, Molecular Formula: C23H26N2O2.C4H6O4, Molecular Weight: 480.56, Appearance: White - Almost white solid crystal powder, Size: 100MG
Catalog Number:
(89151-216)
Supplier:
Enzo Life Sciences
Description:
Topoisomerase I inhibitor
Supplier:
Matrix Scientific
Description:
MF=C11H17N3O2 MW=223.28 CAS=230301-11-8 MDL=MFCD08059268 5G
Supplier:
AMBEED, INC
Description:
Furo[3,4-b]pyridin-5(7H)-one, Purity: 95%, CAS Number: 5657-51-2, Appearance: Solid or Semi-solid or liquid or lump, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
Matrix Scientific
Description:
MF=C13H14Fno2 MW=235.26 Cas=129822-45-3 1G
Supplier:
Spectrum Chemicals
Description:
Gluconolactone, USP is used as a slow release acidifier excipient.
Catalog Number:
(TCN0422-005G)
Supplier:
TCI America
Description:
[Substrate for Phosphatase]
CAS Number: 68189-42-4 MDL Number: MFCD00037009 Molecular Formula: C6H6NO6P Molecular Weight: 461.36 Purity/Analysis Method: >90.0% (T) Form: Crystal Storage Temperature: <0°C
Supplier:
AMBEED, INC
Description:
Irinotecan hydrochloride ≥98%
Catalog Number:
(80057-156)
Supplier:
MilliporeSigma
Description:
p-Nitrophenyl Phosphate, DiTris Salt, excellent substrate for alkaline phosphatase-based ELISA assays.
Supplier:
TCI America
Description:
CAS Number: 1617-90-9
MDL Number: MFCD00078054 Molecular Formula: C21H26N2O3 Molecular Weight: 354.45 Purity/Analysis Method: >98.0% (T) Form: Crystal Color: White Melting point (°C): 232 Specific rotation [a]20/D: 43 deg (C=1, Pyridine)
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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