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12-Deoxyphorbol-13-acetate
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12-Deoxyphorbol-13-acetate
Catalog Number:
(89161-418)
Supplier:
Enzo Life Sciences
Description:
A non-tumor promoting phorbol ester, which acts as a PKC partial agonist. Protects T-lymphoblastoid cells from the killing effects of HIV-1. Upregulates latent HIV-1 provirus expression and inhibits HIV infection and viral spread at the entry/fusion step of viral life cycle. Does not induce tumor formation.
Supplier:
Thermo Scientific Chemicals
Description:
12-Deoxyphorbol 13-acetate; activator of protein kinase C. A weak mouse ear irritant, but lethal at 1ug per mouse
Supplier:
AMBEED, INC
Description:
Phorbol-12-myristate-13-acetate 95%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Phorbol-12-myristate-13-acetate 97%
Supplier:
Thermo Scientific Chemicals
Description:
Activates protein kinase C and promotes skin tumors in mice.
Supplier:
MP Biomedicals
Description:
PMA (Phorbol-12-Myristate-13-Acetate) is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations. PMA’s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC.
PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. Potent tumor promoter; activates protein kinase C in vivo and in vitro. Store at -20 °C. Protect from light.
Catalog Number:
(AAJ61099-MCR)
Catalog Number:
(76203-482)
Supplier:
Enzo Life Sciences
Description:
PKC activator
Catalog Number:
(102987-280)
Supplier:
Adipogen
Description:
Negative control for phorbol ester activation of protein kinase C and studies with PMA (AG-CN2-0010). Might be a reasonable PKC-independent TRPV4 channels agonist.
Supplier:
APOLLO SCIENTIFIC
Description:
2-(6-Chloroimidazo[1,2-a]pyrid-2-yl)acetic acid
Supplier:
Adipogen
Description:
Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin.
Catalog Number:
(77991-700)
Supplier:
LGC STANDARDS
Description:
4Beta-Phorbol 12-Myristate 13-Acetate, TRC, LGC Standards
Supplier:
AMBEED, INC
Description:
4-(4-Methyl-1,3-dioxolan-2-yl)-1,2-methylenedioxybenzene 98% (by GC)
Catalog Number:
(BT216410-25G)
Supplier:
BeanTown Chemical
Description:
CAS: 6413-10-1; EC No: 229-114-0; MDL No: MFCD00152488
Liquid; Molecular Formula: C8H14O4; MW: 174.19
Boiling Point: 98°/12 mmHg; Flash point: 97°C (207°F)
Density (g/mL): 1.09
Catalog Number:
(100269-800)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 22144-77-0 1mg ex. Zygosporium mansonii 255-260[degree]C Room temperature.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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