2-(Difluoromethyl)pyrrolidine+hydrochloride
Catalog Number:
(89152-374)
Supplier:
Enzo Life Sciences
Description:
Na⁺ channel activator.
Supplier:
TCI America
Description:
CAS Number: 103-32-2
MDL Number: MFCD00003018 Molecular Formula: C13H13N Molecular Weight: 183.25 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 307 Melting point (°C): 37 Flash Point (°C): 113
Catalog Number:
(103508-400)
Supplier:
Acros Organics
Description:
Adenosine 5'-triphosphate, Cas number: 34369-07-8, Purity: 98%, Molecular Weight: 551.14, Molecular Formula: C10 H14 N5 Na2 O13 P3. X H2 O, Form: Powder, Solid, Color: White, Synonyms: ATP, disodium salt hydrate, Size: 10G
Catalog Number:
(80055-494)
Supplier:
MilliporeSigma
Description:
A derivative of papaverine that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells
Catalog Number:
(76483-156)
Supplier:
AAT BIOQUEST INC
Description:
Among the ratiometric calcium indicators, Fura-2 and Indo-1 are most commonly used.
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Supplier:
RPI
Description:
ADP [Adenosine-5'-diphosphate, disodium salt dihydrate]
Catalog Number:
(AAJ60040-18)
Supplier:
Thermo Scientific Chemicals
Description:
Used in the cell lysis step of RNA purification. Anionic detergent
Supplier:
MP Biomedicals
Description:
N-Lauroylsarcosine is a derivative of sarcosine . Its sodium salt is anionic surfactant.
Supplier:
Enzo Life Sciences
Description:
Potent and orally active Lck/Src inhibitor.
Catalog Number:
(10261-426)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Catalog Number:
(RC865516)
Supplier:
Ricca Chemical
Description:
1% (w/v) in 20% (v/v) Alcohol with 1% Glacial Acetic Acid. For Basal Cell Carcinoma. Container: Glass.
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Supplier:
AMBEED, INC
Description:
L-(-)-tert-Leucine (H-Tle-OH) 97%
Catalog Number:
(10289-296)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(10289-298)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(10288-048)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(76111-046)
Supplier:
Bioss
Description:
ASH1L is a 2969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.
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