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2,4-Difluoro-3-(methoxymethyl)benzoic+acid
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2,4-Difluoro-3-(methoxymethyl)benzoic+acid
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 532967-21-8, MDL: MFCD07772042
Supplier:
AOB CHEM USA
Description:
(3,4-Difluoro-[1,1'-biphenyl]-2-yl)(methyl)sulfane ≥97%
Supplier:
AOB CHEM USA
Description:
1-Bromo-3,4-Difluoro-2-Methoxy-5-(Methylsulfonyl)Benzene ≥97%
Supplier:
AOB CHEM USA
Description:
(2,6-Difluoro-3-methoxy-5-(methylthio)phenyl)methanol ≥97%
Supplier:
AOB CHEM USA
Description:
(2,3-difluoro-4-methylphenyl)(4-methylpiperazin-1-yl)methanone ≥97%
Catalog Number:
(10801-952)
Supplier:
Rockland Immunochemical
Description:
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) is a basic leucine-zipper (bZip) transcription factor, which regulates amino acid metabolism, DNA damage repair, chromatin remodeling, and apoptosis in response to cellular and ER stress. ATF4 works with various proteins, such as C/EBP homology protein (CHOP), aspargine synthetase (ASNS), and cAMP response element (CRE) among others to mediate cellular stress. ATF4 also regulates glucose homeostasis by suppressing beta-cell proliferation and insulin production. Furthermore, ATF4 targets the histone demethylase JMJD3 to alter chromatin structure and enhance gene transcription in response to amino acid deprivation. Anti-ATF4 is ideal for researchers interested in Cell Signaling, Oncology, Cell Differentiation, and Apoptosis; relevant pathways include MAPK signaling pathways, Activation of cAMP-Dependent PKA, CREB pathways, GPCR pathways and Rho Family GTPases.
Supplier:
AOB CHEM USA
Description:
2-Chloro-2,2-difluoro-1-(4-fluoro-2-methylphenyl)ethanone ≥97%
Supplier:
AOB CHEM USA
Description:
3-Bromo-2,6-difluoro-4'-(trifluoromethoxy)-1,1'-biphenyl ≥95%
Supplier:
AOB CHEM USA
Description:
5-Bromo-4,4'-difluoro-2-methyl-1,1'-biphenyl ≥95%
Supplier:
AOB CHEM USA
Description:
2,2-Difluoro-1-(5-(methylthio)thiophen-2-yl)ethanone ≥97%
Supplier:
AOB CHEM USA
Description:
2-Chloro-2,2-difluoro-1-(2-fluoro-4-methylphenyl)ethanone ≥95%
Supplier:
AOB CHEM USA
Description:
2,3-Difluoro-1,4-benzenediol ≥97%
Supplier:
AOB CHEM USA
Description:
2-Bromo-4,5-difluoro-4'-(trifluoromethoxy)-1,1'-biphenyl ≥95%
Catalog Number:
(77657-614)
Supplier:
AOB CHEM USA
Description:
2,2-Difluoro-1,3-benzodioxole-4-carboxaldehyde ≥97%
Catalog Number:
(102891-726)
Catalog Number:
(10111-590)
Supplier:
Prosci
Description:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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