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DIAGNOSTIC BIOSYSTEMS INC
Supplier:
Diagnostic Biosystems
Description:
This antibody stains with HPV type 16. L1 protein is a major capsid protein of HPV type 16. HPV 6 and 11 have been associated with relatively benign diseases such as genital warts but type 16 and 18 are strongly associated with cervical, vaginal and vulvar malignancies.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with a membrane-bound isoenzyme (Regan and Nagao type) of placental alkaline phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. This antibody is highly specific to PLAP and shows no cross-reaction with other isoenzymes of alkaline phosphatases. It is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA).
Supplier:
Diagnostic Biosystems
Description:
Alpha Fetoprotein (AFP) is a single chain glycoprotein of 70 kDa that is normally expressed in the fetal liver, gastrointestinal tract and yolk sac. This antibody recognizes an epitope of α-fetoprotein present in human and several other species.
Supplier:
Diagnostic Biosystems
Description:
Steptavidin-conjugted Alkaline Phosphatase. Ready To Use Immunostaining Kit Component
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with chains of human IgA. This antibody has been adsorbed to a very high level of specificity.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Mast cells contain a number of preformed chemicals mediators such as histamine, chymase, carboxypeptidase, and proteolytic tryptase. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to 450 kDa (non-reduced) and 170 to 180 kD (reduced) form of thrombospondin. Thrombospondin is a protein from platelet α granules. It is secreted at sites of platelet activation and aggregation and is involved in the differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.
Catalog Number:
(76633-446)
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes heavy chain of human skeletal myosin. It does not stain cardiac or smooth muscle myosin. This antibody stains the fast twitch (type II) isomyosin molecule.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts specifically with a 32 kDa protein similar to the CD8 molecule
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to a cluster of proteins between 19-22 kDa (reduced). VEGF is a homodimeric disulfide-linked glycoprotein involved in angiogenesis, which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability-inducing properties specific for the vascular endothelium.
Supplier:
Diagnostic Biosystems
Description:
Clonepase/4Lj .5Ml
Catalog Number:
(99990-842)
Supplier:
Diagnostic Biosystems
Description:
Clone number UCHL1, This antibody reacts with a 180 kD glycoprotein of CD45 family, occurring on most thymocytes and activated T cells but only on the portion of the resting T cells. It reacts with most thymocytes, a subpopulation of resting cells within both the CD4 and CD8 subsets and mature activated T cells.
Supplier:
Diagnostic Biosystems
Description:
The BCL-2 product is considered to act as an inhibitor of apoptosis. BCL-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. Reactive follicles show no staining for BCL-2, whereas the cells in neoplastic follicles exhibit membrane staining. BCL-2 α oncoprotein has been shown to inhibit apoptosis.
Supplier:
Diagnostic Biosystems
Description:
MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-base mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with desmin protein of 53 kDa. Both striated as well as smooth muscle cells stain well with this antibody. The antibody shows a broad interspecific cross-reactivity, reacting with human.
Supplier:
Diagnostic Biosystems
Description:
Cloner1/69 .5Ml
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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