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2-(2-Methyl-1-piperidinyl)isonicotinic+acid
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2-(2-Methyl-1-piperidinyl)isonicotinic+acid
Supplier:
ALADDIN SCIENTIFIC
Description:
Aminoethyl methacrylate hydrochloride (AMA) is an amine based methacrylic monomer used in the production of polymers and copolymers that are utilized in a wide range of applications, including coatings, adhesives, and medical devices. It is a highly reactive monomer due to the presence of the methacrylate group, which enables it to undergo both free radical polymerization and other polymerization reactions. Due to its biocompatibility and low toxicity, it is widely used in biomedical research and as a crosslinking agent for hydrogels and other biomaterials. It is used in the synthesis of poly (2-aminoethylmethacrylate), a biocompatible cationic polymer widely used in the biomedical field.Application:2-Aminoethylmethacrylate hydrochloride(AMA) can be used as a precursor to synthesize: Homo and copolymer brushes of AMA, which can be used to tune the electrochemical properties of silicon wafers. Poly(3-hydroxybutyrate) based polyurethane/urea composite scaffolds for tissue engineering applications. Antimicrobial bacterial cellulose/poly (AMA) nanocomposites. Polymer incorporation imparts mechanical properties and antimicrobial activity to bacterial cellulose membranes.It can also be used for the efficient functionalization of hyaluronic acid via triazine-mediated amidation.
Catalog Number:
(10082-134)
Supplier:
Proteintech
Description:
Four-and-a-half LIM domains 1 (FHL1), a member of the FHL protein family, which composed of FHL 1, 2, 3, 4 and ACT (activator of CREM), and characterized by an N-terminal half LIM domain followed by four complete LIM domains. FHL1 may contribute to sarcomere synthesis, assembly and biomechanical stress sensing. FHL1 is also a methylation-silenced tumor-suppressor gene on chromosome X in gastrointestinal cancers, which contributes to the formation of an epigenetic field for cancerization. FHL1(10991-1-AP) is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. This is a rabbit polyantibody raised against full length of human FHL1.
Catalog Number:
(10751-260)
Supplier:
Prosci
Description:
MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Supplier:
BeanTown Chemical
Description:
CAS: 616-38-6; EC No: 210-478-4; MDL No: MFCD00008420; RTECS: FG0450000
UN No: UN1161; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: (CH3O)2CO; MW: 90.08
Melting Point: 2-4°; Boiling Point: 90°; Flash point: 16°C (61°F)
Density (g/mL): 1.069; Refractive Index: 1.368
Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 5927-18-4; EC No: 227-663-0; MDL No: MFCD00008452
Liquid; Linear Formula: (CH3O)2P(O)CH2COOCH3; Molecular Formula: C5H11O5P; MW: 182.11
Boiling Point: 265-268°; Flash point: 70°C (158°F)
Density (g/mL): 1.125; Refractive Index: 1.437
Catalog Number:
(80108-306)
Supplier:
MilliporeSigma
Description:
An active metabolite of the nonsteroidal, anti-inflammatory drug sulindac (80058-684)
Catalog Number:
(103007-966)
Supplier:
Anaspec Inc
Description:
This peptide is a histone H3 trimethylated at lysine 4 and is associated with transcription, specifically marking the transcription start site of actively transcribed genes. This peptide can be demethylated by Jumonji AT-rich interactive domanin 1 (JARID1) or by lysine demethylase 5 (KDM5) family of lysine demethylases.
Sequence: ART-K(Me3)-QTARKSTGGKAPRKQLA MW: 2296.6 Da % peak area by HPLC: 95 Storage condition: -20 °C
Catalog Number:
(75929-806)
Supplier:
Rockland Immunochemical
Description:
The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Catalog Number:
(75929-758)
Supplier:
Rockland Immunochemical
Description:
Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is a recently discovered amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues (such as H3-K4) is associated with active transcription. LSD1 associates with various proteins, including HDAC1/2, CoREST, and BHC80, that act to regulate LSD1 activity in vivo, and in a histone H3-K4-specific methylase complex that is involved in transcriptional regulation. Experiments have shown that CoREST, a SANT domain-containing corepressor acts to enhance LSD1 activity, while BHC80, a PHD domain-containing protein, inhibits CoREST/LSD1 activity in vitro. LSD1-mediated histone demethylation thus may have significant effects on gene expression.
Catalog Number:
(TCH0965-25G)
Supplier:
TCI America
Description:
CAS Number: 110878-71-2
MDL Number: MFCD02093474 Molecular Formula: C11H15NO Molecular Weight: 177.25 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 225
Catalog Number:
(H-6334.0500BA)
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
Supplier:
AMBEED, INC
Description:
3-Methylbenzofuran-2-carboxylic acid, Purity: 98%, CAS Number: 24673-56-1, Appearance: Beige to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 10G
Catalog Number:
(75933-696)
Supplier:
Rockland Immunochemical
Description:
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB9, also known as ZNF919, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB9, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB9 may act as a transcriptional repressor or be involved in tumorigenesis.
Supplier:
BeanTown Chemical
Description:
CAS: 121-43-7; EC No: 204-468-9; MDL No: MFCD00008346; RTECS: ED5600000
UN No: UN2416; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: B(OCH3)3; Molecular Formula: C3H9BO3; MW: 103.92
Melting Point: -34°; Boiling Point: 68-69°; Flash point: -8°C (18°F)
Density (g/mL): 0.932; Refractive Index: 1.346
Moisture Sensitive
Catalog Number:
(75929-760)
Supplier:
Rockland Immunochemical
Description:
Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is a recently discovered amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues (such as H3-K4) is associated with active transcription. LSD1 associates with various proteins, including HDAC1/2, CoREST, and BHC80, that act to regulate LSD1 activity in vivo, and in a histone H3-K4-specific methylase complex that is involved in transcriptional regulation. Experiments have shown that CoREST, a SANT domain-containing corepressor acts to enhance LSD1 activity, while BHC80, a PHD domain-containing protein, inhibits CoREST/LSD1 activity in vitro. LSD1-mediated histone demethylation thus may have significant effects on gene expression.
Supplier:
AMBEED, INC
Description:
2-Amino-4-methylbenzoic acid 97%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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