2-[(Prop-2-ynyloxy)methyl]oxirane
Catalog Number:
(TCD3239-25G)
Supplier:
TCI America
Description:
CAS Number: 50729-75-4
Molecular Formula: C19H33N7
Molecular Weight: 359.52
Purity/Analysis Method: <gt/>99.0% (T)
Form: Crystal
Melting point (°C): 193
Flash Point (°C): 270
Supplier:
Matrix Scientific
Description:
{5,13}]-TRIDECA-1(13),5,7,9,11- PENTAEN-3-YL}BUTANOATE
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Supplier:
Matrix Scientific
Description:
MF=C10H15N3O2S MW=241.31 CAS=104481-24-5 MDL=MFCD09910379 250MG
Catalog Number:
(101811-790)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 021332-500MG , MDL Number: MFCD00979774
Supplier:
BeanTown Chemical
Description:
CAS: 615-79-2; EC No: 210-447-5; MDL No: MFCD00009124
Liquid; Linear Formula: CH3COCH2COCOOCH2CH3; Molecular Formula: C7H10O4; MW: 158.15
Melting Point: 16-18°; Boiling Point: 101-103°/12 mmHg; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 1.126; Refractive Index: 1.470
Catalog Number:
(101831-514)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031344-500MG , MDL Number: MFCD03211054
Supplier:
AMBEED, INC
Description:
10-Ethyl-3,7,8-trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, Purity: 97%, CAS Number: 67767-38-8, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 50MG
Catalog Number:
(101832-796)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031986-500MG , MDL Number: MFCD10688001
Catalog Number:
(101832-128)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031651-500MG , MDL Number: MFCD03210972
Supplier:
Thermo Scientific Chemicals
Description:
H-DL-Val-OEt. HCl. Grade: 99. Melting Point Cca 94*. Boiling Point C: NA. C7H16ClNO2. 23358-42-1.
Catalog Number:
(TCD0053-100MG)
Supplier:
TCI America
Description:
CAS Number: 148-51-6
MDL Number: MFCD00051296 Molecular Formula: C8H11NO2 Molecular Weight: 189.64 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 274
Catalog Number:
(101916-688)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059011-5G , MDL Number: MFCD00126316
Catalog Number:
(101934-290)
Supplier:
Matrix Scientific
Description:
MF=C18H25Cln2O2S MW=368.93 250Mg
Catalog Number:
(101920-182)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060530-500MG , MDL Number: MFCD16038572
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