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2-(Boc-amino)pyridine
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2-(Boc-amino)pyridine
Supplier:
Matrix Scientific
Description:
MF=C7H8N2O2 MW=152.15 Cas=67515-76-8 5G
Supplier:
Adipogen
Description:
Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.
Supplier:
Adipogen
Description:
RO495 is a very potent TYK2 inhibitor with a IC(50) of 1.5nM on TYK2 as tested in cell-based pharmacological assays including the compound-mediated effects on STAT5 phosphorylation in Set-2 lysates or IL-12 stimulation of NK92 using the Meso Scale Discovery (MSD) technology.
Catalog Number:
(77405-096)
Supplier:
APOLLO SCIENTIFIC
Description:
3-(2-Pyridyl)-D-alanine
Supplier:
Matrix Scientific
Description:
MF=C8H11BRN2O2S MW=279.16 CAS=405939-39-1 MDL=MFCD07368614 5G
Catalog Number:
(77746-737)
Supplier:
AMBEED, INC
Description:
H-4-Pal-OH·2HCl ≥98%
Supplier:
Matrix Scientific
Description:
MF=C13H21N5O2 MW=279.34 CAS=1208542-95-3 MDL=MFCD11040180 5G
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00006324
Beilstein Registry No.: 108735
Supplier:
APOLLO SCIENTIFIC
Description:
H-4-Pal-OH·2HCl 98%
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
CHIR 99021 is an aminopyrimidine derivate that is a selective and potent inhibitor of glycogen synthase kinase 3 (GSK-3)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031268-5G , MDL Number: MFCD03541052
Catalog Number:
(101879-730)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 047377-1G , MDL Number: MFCD11100244
Supplier:
AMBEED, INC
Description:
2-Amino-3-chloropyridine 98%
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 62476-56-6, MDL: MFCD00023417
Supplier:
MP Biomedicals
Description:
Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. This product exhibits metal binding properties. Hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy. Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics). Very slightly soluble in cold water (0.0016 mg/mL at 25 °C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides and carbonates. Soluble in hot dilute HCl and H2SO4.
Supplier:
Adipogen
Description:
Building block for synthesis. DPA is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. The amino nitrogen of the DPA group is a good candidate as an electron donor in either photoinduced electron transfer or photoinduced charge transfer (PET or PCT) sensors. Zn(II)–DPA complexes are widely used in anion recognition and sensing.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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