2-[(3-Methoxypropyl)amino]isonicotinic+acid
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
L-Glutamic acid 5-benzyl ester 99%
Supplier:
AMBEED, INC
Description:
Boc-Aib-OH 97%
Supplier:
PeproTech, Inc.
Description:
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(R)-N-Boc-allylglycine 95%, 98% ee
Supplier:
AMBEED, INC
Description:
2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid, Purity: 98%, CAS Number: 220991-20-8, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 10mg
Supplier:
Matrix Scientific
Description:
MF=C4H6N4O2 MW=142.12 CAS=3641-14-3 MDL=MFCD02695363 5G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041282-25G , MDL Number: MFCD00002635
Supplier:
AMBEED, INC
Description:
2-(2-Chlorophenyl)glycine 99+%
Supplier:
PeproTech, Inc.
Description:
CD40, a member of the TNF receptor superfamily, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to “immunodeficiency with hyper-IgM”, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant Human soluble CD40 ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L. Manufactured using all Animal-Free reagents.
Supplier:
Adipogen
Description:
Catabolite of thymine. Precursor for 3-Hydroxyisobutyric acid synthesis. Small molecule myokine. Browning inducer of white adipose tissue (WAT) into brown adipose tissue (BAT). PGC-1alpha-mediated and exercise-triggered nonadrenergic activator of the thermogenic program in WAT. Increases the expression of brown adipocyte-specific genes (browning) in white adipocytes and beta-oxidation in hepatocytes through a PPARalpha-mediated mechanism. Induces a brown adipose-like phenotype in human pluripotent stem cells and improves glucose homeostasis. Enhances fatty acid oxidation and reduces body weight in mice through an increased production of leptin by the white adipose tissue (WAT). Inhibits Agxt2-mediated metabolism of dimethylarginines. Partial agonist of the glycine receptor (GlyR).
Catalog Number:
(103662-672)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human BCCIP (AAH09771.1) (Met1-Val314) was expressed with two additional amino acids (Gly and Pro) at the N-terminus.
Catalog Number:
(10303-518)
Supplier:
Bioss
Description:
AHNAK is a 5,890 amino acid protein encoded by the human gene AHNAK. The intronless AHNAK gene is located on human chromosome 11q12 and has three main structural regions: the 251 amino acid N-terminus, a large central region of 4390 amino acids with multiple repeated units of about 128 amino acids in length, and the 1002 amino acid C-terminus. The central region seems to have antiparallel beta-strands connected by intervening loops. Several putative regulatory elements are clustered within the C-terminal region, including nuclear export localization signals, a leucine zipper, and potential phosphorylation sites for Akt1 and PKC. AHNAK is believed to be an important signalling molecule involved in a wide range of physiological activities and may be required for neuronal cell differentiation.. AHNAK also appears to influence b-adrenergic regulation of cardiac L-type Ca2+ channel function.
Catalog Number:
(10257-662)
Supplier:
Bioss
Description:
Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
Supplier:
AMBEED, INC
Description:
H-Gly(Ally)-OH, Purity: 98%, CAS Number: 16338-48-0, Appearance: Form: powder Colour: white, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 10g
Catalog Number:
(10062-662)
Supplier:
Prosci
Description:
18 amino acid peptide near the carboxy terminus of human KREMEN1.
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