2-[(Acetylthio)methyl]-3-phenylpropionic+acid
Catalog Number:
(TCM1079-005ML)
Supplier:
TCI America
Description:
CAS Number: 6124-79-4
MDL Number: MFCD00191546 Molecular Formula: C5H6O2 Molecular Weight: 98.10 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 113 Flash Point (°C): 95 Specific Gravity (20/20): 1.12
Catalog Number:
(PI85190)
Supplier:
Invitrogen
Description:
The Pierce™ Dimethylsulfoxide (DMSO) is a sequencing-grade preparation with high purity for use in traditional amino acid analyzers and other high-volume applications.
Supplier:
BeanTown Chemical
Description:
CAS: 431-47-0; EC No: 207-074-5; MDL No: MFCD00000417
UN No: UN2924; Haz Class: 3(8); Packing Group: II
Liquid; Linear Formula: CF3COOCH3; Molecular Formula: C3H3F3O2; MW: 128.05
Melting Point: -78°; Boiling Point: 43-44°; Flash point: -20°C (-4°F)
Density (g/mL): 1.273; Refractive Index: 1.291
Moisture Sensitive
Catalog Number:
(103008-018)
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 1 to 10 di-methylated at Lys-4.
Sequence:ART-K(Me2)-QTARKS MW:1174.3 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(77669-482)
Supplier:
AMBEED, INC
Description:
AZD-6482 ≥98%
Supplier:
AMBEED, INC
Description:
1-Methylimidazole-5-boronic acid pinacol ester 95%
Supplier:
AMBEED, INC
Description:
3-Methoxycarbonyl-5-trifluoromethoxylphenylboronic acid, pinacol ester 95%
Catalog Number:
(77274-414)
Supplier:
AMBEED, INC
Description:
3-Methylquinoxaline-5-carboxylic acid, Purity: 98%, CAS Number: 904813-39-4, Appearance: White to yellow to purple powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 100mg
Supplier:
BeanTown Chemical
Description:
CAS: 1458-18-0; EC No: 215-947-7; MDL No: MFCD00010431
Powder; Molecular Formula: C6H5Cl2N3O2; MW: 222.03
Melting Point: 230-233°
Supplier:
AMBEED, INC
Description:
(Tetrahydrofuran-2-yl)methyl acrylate, Purity: 98% (GC)(stabilized with MEHQ), CAS Number: 2399-48-6, Appearance: Form: liquid Colour: colourless, Storage: Sealed in dry, Room Temperature, Size: 100G
Supplier:
AMBEED, INC
Description:
7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate, Purity: 95% (stabilized with HQ), CAS Number: 64630-63-3, Appearance: Form: liquid/Colour: Colorless - Yellow, Storage: Inert atmosphere, Room Temperature, Size: 5g
Catalog Number:
(AAJ67377-AC)
Supplier:
AMBEED, INC
Description:
Losartan carboxylic acid, Purity: 97%, CAS Number: 124750-92-1, Appearance: solid, Storage: Inert atmosphere, 2-8 C, Size: 1mg
Supplier:
AMBEED, INC
Description:
(R)-3-Amino-4-methoxy-4-oxobutanoic acid, Purity: 95%, CAS Number: 65414-78-0, Appearance: White to off-white solid, Storage: Sealed in dry, Room Temperature, Size: 100G
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
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