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Catalog Number:
(102519-978)
Supplier:
Matrix Scientific
Description:
MF=C21H40N2O5 MW=400.56 MDL=MFCD09260875 1G
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Catalog Number:
(102894-574)
Supplier:
AMBEED, INC
Description:
(R)-2-(1-(2-(2-Methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoic acid, Purity: 97%, CAS Number: 1434635-54-7, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8C, Size: 5MG
Supplier:
AMBEED, INC
Description:
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid, Purity: 98%, CAS Number: 197632-76-1, Appearance: Solid, Storage: Sealed in dry, 2-8C, Size: 250MG
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042759-5G , MDL Number: MFCD00124778
Supplier:
AOB CHEM USA
Description:
2-(Methylcarbamoyl)pyridine-5-boronic acid pinacol ester ≥97%
Catalog Number:
(77157-554)
Supplier:
AMBEED, INC
Description:
Methyl 4-(aminomethyl)cyclohexanecarboxylate hydrochloride, Purity: 98%, CAS Number: 54640-02-7, Appearance: White to off-white powder or crystals, Storage: Inert atmosphere, Room Temperature, Size: 250mg
Catalog Number:
(76480-500)
Supplier:
AAT BIOQUEST INC
Description:
Pyronin Y is widely used in combination with methyl green to selectively and differentially stain nucleic acids following polyacrylamide gel electrophoresis.
Supplier:
TCI America
Description:
CAS Number: 39830-66-5
MDL Number: MFCD00191222 Molecular Formula: C10H9NO2 Molecular Weight: 175.19 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 71
Supplier:
Honeywell Research Chemicals
Description:
We are your supplier of high-quality lab reagents and chemicals for analytical and chemistry laboratories:
Catalog Number:
(77691-435)
Supplier:
LGC STANDARDS
Description:
Acetic acid-methyl ester 1000 µg/mL in Methanol, Dr. Ehrenstorfer, LGC Standards
Supplier:
TCI America
Description:
CAS Number: 22262-60-8
MDL Number: MFCD00011534 Molecular Formula: C5H8Br2O2 Molecular Weight: 259.93 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 62 Flash Point (°C): 113 Specific Gravity (20/20): 1.85
Supplier:
AMBEED, INC
Description:
4-(N-(4-Cyclohexylbenzyl)-2-((2,3,4,5,6-pentafluoro-N-methylphenyl)sulfonamido)acetamido)benzoic acid, Purity: 98+%, CAS Number: 1456632-40-8, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 C, Size: 1mg
Supplier:
AMBEED, INC
Description:
O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)(methyl)carbamothioate, Purity: 98%, CAS Number: 88678-31-3, Appearance: Form: Crystal - Powder / Colour: White - Very pale yellow, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 25G
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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