2-Bromo-3,6-dimethoxybenzoic+acid
Supplier:
Adipogen
Description:
IL-36Ra/IL-1F5 is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9). These cytokines bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are target of the IL-36 interleukins leading to a Th1 response. Recently mutations that affect the levels and the activity of IL-36Ra have been found in patients with pustular psoriasis, leading to enhanced production of inflammatory cytokines (IL-8 in particular) by keratinocytes.
Supplier:
Thermo Scientific Chemicals
Description:
A vitamin in the Vitamin B-6 family
Supplier:
TCI America
Description:
CAS Number: 18531-94-7
MDL Number: MFCD00004068 Molecular Formula: C20H14O2 Molecular Weight: 286.33 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 210 Specific rotation [a]20/D: 36 deg (C=1, THF)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 011260-25G , MDL Number: MFCD03206481
Supplier:
TCI America
Description:
CAS Number: 13035-19-3
MDL Number: MFCD02179399 Molecular Formula: C5H12N2 Molecular Weight: 100.17 Purity/Analysis Method: >96.0% (GC,T) Form: Crystal Boiling point (°C): 36 Flash Point (°C): 48 Freezing point (°C): 25
Supplier:
AOB CHEM USA
Description:
2,5-Dibromo-6-fluorobenzonitrile ≥97%
Catalog Number:
(101918-664)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059622-1G , MDL Number: MFCD14698561
Catalog Number:
(101829-182)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 029953-500MG , MDL Number: MFCD04140918
Catalog Number:
(101846-456)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038911-500MG , MDL Number: MFCD09669476
Supplier:
TCI America
Description:
CAS Number: 1887-02-1
MDL Number: MFCD00036127 Molecular Formula: C6H4O6 Molecular Weight: 216.06 Form: Crystal Color: Yellow Green
Catalog Number:
(10475-548)
Supplier:
Bioss
Description:
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052651-500MG , MDL Number: MFCD13562331
Supplier:
BeanTown Chemical
Description:
CAS: 652-67-5; EC No: 211-492-3; MDL No: MFCD00064827; RTECS: LZ4380000
Flakes; Molecular Formula: C6H10O4; MW: 146.14
Melting Point: 60-63°
Optical Rotation: [α]20/D +45.2°, c = 3 in water
Hygroscopic
Supplier:
Dickies
Description:
Dickies® style 83294.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054243-1G , MDL Number: MFCD14581638
Supplier:
Strem Chemicals Inc
Description:
CAS #: 562-76-5. Size: 5g.
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