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4-Bromo-5-(trifluoromethyl)-1H-indazole
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4-Bromo-5-(trifluoromethyl)-1H-indazole
Catalog Number:
(80055-978)
Supplier:
MilliporeSigma
Description:
A natural dietary compound reported to have anticarcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50=3.7µM). Inhibits Ca2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
Catalog Number:
(77624-364)
Supplier:
AMBEED, INC
Description:
2,4-Dibromoanisole ≥99%
Supplier:
AOB CHEM USA
Description:
2,4-Dimethoxytoluene ≥97%
Catalog Number:
(102991-276)
Supplier:
Adipogen
Description:
CD14/TLR4 antagonist. Inhibitor of sterile inflammation. Synthetic TLR4/CD14 ligand with TLR4 modulating activities in vitro, and conferring protection against TLR4/CD14-mediated tissue damage and inflammation in vivo. Useful to explore CD14- dependent and TLR4-independent pathways and TLR4 activation by endogenous ligands (e.g. hyaluronic acid oligosaccharides, oxLDL, HMGB1) in sterile inflammation. Shown to inhibit neuropathic pain, secondary necrosis of acute drug-induced liver failure and vascular inflammation, and abdominal aortic aneurysm by blocking non-hematopoietic TLR4 signaling. Useful tool, where inhibition of sterile (auto-) inflammation is desired, without compromising TLR4’s key role in the defense of pathogens.
Supplier:
Adipogen
Description:
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.
Supplier:
Spectrum Chemicals
Description:
2,4-Dinitrophenylhydrazine is a chemical compound that is usually supplied as a wet red-to-orange solid that is shock sensitive. It is used in Brady's test to detect the carbonyl functionality of an aldehyde or ketone functional group
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
α,2,4-Trichlorotoluene 99%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Xylenol 99%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Difluorobenzylamine 98%
Supplier:
AMBEED, INC
Description:
2,4-Dimethoxyquinoline 95%
Catalog Number:
(MFLX34002-24)
Supplier:
VWR International
Description:
Connect even the smallest tubing with a leak-free seal from vacuum to pressure.
Supplier:
AMBEED, INC
Description:
2,4-Dichloroquinoline 98%
Catalog Number:
(102841-370)
Supplier:
Matrix Scientific
Description:
2,4-Dichloro-6-nitroquinoline 97
Supplier:
AMBEED, INC
Description:
Ethyl 2,4-dichlorophenylacetate 98%
Supplier:
AMBEED, INC
Description:
5-Bromo-2,4-difluoroaniline 98%
Supplier:
AMBEED, INC
Description:
2,4-Dibromoiodobenzene 97%, Ambeed.Inc
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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