3-(3,4-Dimethylphenoxy)pyrrolidine+hydrochloride
Supplier:
TCI America
Description:
CAS Number: 104-10-9
MDL Number: MFCD00007922 Molecular Formula: C8H11NO Molecular Weight: 137.18 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 255 Melting point (°C): 108
Supplier:
Matrix Scientific
Description:
MF=C9H18F3Nosi MW=241.33 Cas=77377-52-7 MDL=MFCD00009671 ,25G
Supplier:
TCI America
Description:
CAS Number: 92-50-2
MDL Number: MFCD00020575 Molecular Formula: C10H15NO Molecular Weight: 165.24 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 268 Flash Point (°C): 132 Freezing point (°C): 34
Supplier:
TCI America
Description:
CAS Number: 137-58-6
MDL Number: MFCD00026733 Molecular Formula: C14H22N2O Molecular Weight: 234.34 Purity/Analysis Method: >99.0% (HPLC,T) Form: Crystal Boiling point (°C): 182 Melting point (°C): 69
Supplier:
Adipogen
Description:
The BCR-ABL oncogene triggers intracellular signaling, activating multiple transduction cascades, promoting the growth, proliferation and survival of hematopoietic cells. BCR-ABL plays a role in defective DNA repair, alteration of cellular adhesion and inhibition of apoptosis. Degregulated BCR-ABL tyrosine kinase activity is the molecular marker for CML. Inhibiting BCR-ABL tyrosine kinase activity leads to the induction of apoptosis and inhibits cellular proliferation in vitro and there are various BCR-ABL isoforms with differing activity levels as well. Dasatinib (BMS-354825, Sprycel®) is a potent multi-target kinase inhibitor of BCR-ABL. Dasatiinib performs better against ABL kinase than earlier drugs such as imatinib, and Dasatinib also is effective against SRC family of kinases, and other receptor kinases such as EPHA2, PDGFR, and c-Kit. Dasatinib's inhibiting potential against Src family kinase members is greater (IC(50) 0.5nM) than its inhibitory activity against ABL (1nM).
Supplier:
MP Biomedicals
Description:
Tricine was first prepared by Good for use as a buffer for chloroplast reactions. It is structurally similar to Tris, but is much less inhibitory at high concentrations. For ATP assays using firefly luciferase, tricine buffer at 25 mM was found to be the best of ten common buffers tested.
Tricine is used as buffer component for separation of low molecular weight peptides. Tricine can be used in cryopreservation medium for the preservation of tissues and organs. Cryopreservation depends on the physical and chemical characteristics of the preservation medium used. The pH values and pK values for tricine/DMSO mixtures has been reported down to -20 °C. Tricine has been found to be an efficient scavenger of hydroxyl radicals in a study of radiation-induced membrane damage. Tricine is typically the buffer of choice in SDS-PAGE systems when separating proteins in the range of 1 to 100 kDa. A buffer may be prepared by titrating with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH.
Catalog Number:
(77199-554)
Supplier:
AMBEED, INC
Description:
1-(2,6-Dichlorophenyl)ethanol, Purity: 97%, CAS Number: 53066-19-6, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 1g
Supplier:
AMBEED, INC
Description:
N-Methyl-2-fluoroaniline, Purity: 98%, CAS number: 1978-38-7, Appearance: Form: liquid / Colour: Colorless - Slightly pale yellow - Brown, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 10G
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Acetylamino-5-bromo-6-methylpuridine is used to prepare palladium-catalyzed cross-coupling reactions of pyridylboronic acids with heteroaryl halides.
Catalog Number:
(77278-262)
Supplier:
AMBEED, INC
Description:
N-Methyl-1,2-benzenediamine dihydrochloride, Purity: 99%, CAS Number: 25148-68-9, Appearance: Form: Crystal - Powder, Storage: Inert atmosphere, Room Temperature, Size: 100g
Supplier:
MP Biomedicals
Description:
Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin.
Supplier:
MP Biomedicals
Description:
Storage: Room Temperature
2-Mercaptoethanol is a hybrid of ethylene glycol and 1,2-ethanedithiol. It is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its diminished vapor pressure, its odour, while unpleasant, is less objectionable than related thiols. 2-Mercaptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis (typically used in SDS-PAGE sample buffer at 5% concentration). Also it reduces excess oxidative polymerization of catalysts. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure. In solution, 2-mercaptoethanol is readily oxidized in air to a disulfide, especially at alkaline pH. Because of this property, it is widely used to protect proteins, enzymes in particular, from becoming inactive. An excess of 2-mercaptoethanol (generally used at 0.01 M) will maintain the protein thiol groups in their reduced state.
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Aminophenethyl alcohol undergoes one-pot cyclization with carboxylic acids in the presence of PPh3, CCl4 and NEt3 to yield N-acyl indolines.2-Aminophenethyl alcohol was used in the synthesis of: 1. indole derivatives. 2. N-(cyanothioformyl)indoline. 3. dihydro-3,1-benzoxazepine.
Supplier:
AMBEED, INC
Description:
2-(2-Chlorophenyl)ethanol, Purity: 98%, CAS Number: 19819-95-5, Appearance: Form: liquid/Colour: Colorless - Slightly pale yellow, Storage: Sealed in dry, Room Temperature, Size: 5g
Supplier:
TCI America
Description:
CAS Number: 110-70-3
MDL Number: MFCD00008290 Molecular Formula: C4H12N2 Molecular Weight: 88.15 Purity/Analysis Method: >97.0% (GC,T) Form: Clear Liquid Boiling point (°C): 119 Flash Point (°C): 26 Specific Gravity (20/20): 0.82
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