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3-[(2,3-Dimethylphenoxy)methyl]pyrrolidine+hydrochloride
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3-[(2,3-Dimethylphenoxy)methyl]pyrrolidine+hydrochloride
Supplier:
Adipogen
Description:
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Supplier:
AOB CHEM USA
Description:
(3-Chloro-5-fluorophenyl)trimethylsilane ≥95%
Supplier:
AMBEED, INC
Description:
Nigericin sodium salt ≥98%
Catalog Number:
(TCB0686-025ML)
Supplier:
TCI America
Description:
CAS Number: 513-53-1
MDL Number: MFCD00004865 Molecular Formula: C4H10S Molecular Weight: 90.18 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 84 Melting point (°C): -165 Flash Point (°C): -23 Specific Gravity (20/20): 0.83
Catalog Number:
(77245-964)
Supplier:
AMBEED, INC
Description:
(3aS,4S,6R,6aR)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid, Purity: 97%, CAS Number: 54622-95-6, Appearance: White to off white to yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 250mg
Catalog Number:
(10387-544)
Supplier:
Bioss
Description:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Supplier:
TCI America
Description:
CAS Number: 80-59-1
MDL Number: MFCD00066864 Molecular Formula: C5H8O2 Molecular Weight: 100.12 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Color: White Boiling point (°C): 82 Melting point (°C): 64 Flash Point (°C): 101 Storage Temperature: 0-10°C
Supplier:
Thermo Scientific Chemicals
Description:
An aminocyclitol antibiotic that binds to the 30S ribosomal subunit of bacteria and interrupts protein synthesis
Supplier:
Adipogen
Description:
Slow, tight binding and competitive aminopeptidase (AP) inhibitor. Inhibits cytosolic leucine aminopeptidase, microsomal aminopeptidase M and bacterial leucine aminopeptidase, human serum aminopeptidase A (AP-A), aminopeptidase N (AP-N), tyrosine aminopeptidase, but not aminopeptidase B (AP-B).
Catalog Number:
(76084-920)
Supplier:
Bioss
Description:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Supplier:
Adipogen
Description:
NVP-BEZ235 is an imidazo[4,5-c]quinoline derivative that inhibits PI3K and mTOR kinase activity by binding to the ATP-binding cleft of these enzymes. In cellular settings using human tumor cell lines, this molecule is able to effectively and specifically block the dysfunctional activation of the PI3K pathway, inducing G1 arrest at IC(50) values 3-10nM in biological cell growth and viability assays. In addition NVP-BEZ235 shows effective IC(50) values in in vitro tests against mTor and PI3K family members of 10nM.
Catalog Number:
(10387-590)
Supplier:
Bioss
Description:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Supplier:
ALADDIN SCIENTIFIC
Description:
Product Description2-Amino-3-formylchromone (2-Amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde) is a benzopyran derivative. It is a bicyclic heterocyclic molecule made up of a benzene ring fused to a heterocyclic pyran ring. It undergoes condensation with (R)-2-amino-2-phenylethanol to afford Schiff base ligand, which forms complexes with Cu(NO3)2 and Zn(NO3)2Product Application2-Amino-3-formylchromone may be used in the preparation of the following:• chiral Schiff base ligands (R)/(S)-2-amino-3-(((1-hydroxypropan-2-yl)imino)methyl)-4H-chromen-4-one• hydrazone derivatives, required for the synthesis of heterocyclic Schiff′s bases having antimicrobial activity[• N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-3,5-dimethyl-benzofuran-2-carboxamide• N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-1,4-dihydro-chromono [2,3-b]pyrrole-2-carboxamide• 6-chloro-3-{[4-(2-thioxo-3,6-dihydro-2H-1,3,4-thiadiazin-5-ylamino)phenylimino] methyl}- 4-oxo-4H -chromene• 3¬-(2-amino¬-4¬-oxo¬-4H¬-chromen¬-3-¬yl)methylidene)¬-6-¬ ethyl-¬2H-¬pyrano[3,2-¬c]quinolone-¬2,4,5(3H,6H)-trione
Supplier:
Adipogen
Description:
Nigericin is a high-affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+.
Supplier:
Adipogen
Description:
XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)
Catalog Number:
(101808-742)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 019760-500MG , MDL Number: MFCD03986071
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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