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Supplier:
PeproTech, Inc.
Description:
Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as an activin antagonist whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant Human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.
Catalog Number:
(103633-286)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the Influenza A virus (A/duck/Eastern China/11/2009(H6N6)) hemagglutinin (AEF59343.1) (Met1-Arg344), termed as HA1, was expressed with a polyhistidine tag at the C-terminus.
Catalog Number:
(10278-202)
Supplier:
Bioss
Description:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 39 (LRRC39) is a 335 amino acid protein that contains nine LRR repeats and exists as two alternatively spliced isoforms.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(S)-N-Boc-α-ethylalanine 98%, 98% ee
Catalog Number:
(10073-092)
Supplier:
Prosci
Description:
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.
Catalog Number:
(AAH61640-06)
Supplier:
Thermo Scientific Chemicals
Description:
2-(Diphenylphosphino)biphenyl, 98%
Catalog Number:
(10477-548)
Supplier:
Bioss
Description:
HkRP3, also known as CCDC88B (coiled-coil domain-containing protein 88B) or BRLZ (brain leucine zipper domain-containing protein), is a 1,476 amino acid protein that belongs to the CCDC88 family. Members of the hook-related protein family are characterized by the presence of a C-terminal hook-related domain and an N-terminal potential microtubule binding domain. HkRP3 may be involved in the linkage of various organelles to microtubules, and exists as six alternatively spliced isoforms. The gene encoding HkRP3 maps to human chromosome 11q13.1 and mouse chromosome 19 A. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Supplier:
BeanTown Chemical
Description:
CAS: 88878-50-6; MDL No: MFCD11053423
Solid; Molecular Formula: C24H35FO2; MW: 374.54
Melting Point: 64-66°
Supplier:
Matrix Scientific
Description:
3-(2-Biphenyl)-1-propene ≥97%
Catalog Number:
(76107-104)
Supplier:
Bioss
Description:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion, and drug extrusion and delivery. CCDC83 (coiled-coil domain-containing protein 83), also known as HSD9, is 413 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding CCDC83 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Catalog Number:
(10842-814)
Supplier:
Enzo Life Sciences
Description:
Digoxigenin-labeled nucleotide suitable for non-radioactive labeling of DNA probes.
Catalog Number:
(EM1.04593.0025)
Supplier:
BeanTown Chemical
Description:
CAS: 406-95-1; MDL No: MFCD00198018
UN No: UN3272; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: CH3COOCH2CF3; Molecular Formula: C4H5F3O2; MW: 142.08
Flash point: 11°C (51°F)
Density (g/mL): 1.258
Catalog Number:
(10477-756)
Supplier:
Bioss
Description:
HkRP3, also known as CCDC88B (coiled-coil domain-containing protein 88B) or BRLZ (brain leucine zipper domain-containing protein), is a 1,476 amino acid protein that belongs to the CCDC88 family. Members of the hook-related protein family are characterized by the presence of a C-terminal hook-related domain and an N-terminal potential microtubule binding domain. HkRP3 may be involved in the linkage of various organelles to microtubules, and exists as six alternatively spliced isoforms. The gene encoding HkRP3 maps to human chromosome 11q13.1 and mouse chromosome 19 A. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Supplier:
BeanTown Chemical
Description:
CAS: 762-21-0; EC No: 212-095-8; MDL No: MFCD00009186
UN No: UN1760; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: CH3CH2O2CC≡CCO2CH2CH3; Molecular Formula: C8H10O4 ; MW: 170.16
Boiling Point: 107-110°/11 mmHg; Flash point: 94°C (201°F)
Density (g/mL): 1.063; Refractive Index: 1.443
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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