4-Ethoxy-3-formyl-5-methoxybenzoic+acid
Catalog Number:
(102987-844)
Supplier:
Adipogen
Description:
Specific protein kinase C (PKC) activator. Selective activator of PKC isoforms, like PKCtheta in T cells. Antiproliferative and proapoptotic (necrotic). Immunostimulant. Chemotherapeutic. Anticancer compound. Efficacious agent against actinic kerastosis. Antileukemic.
Supplier:
Adipogen
Description:
A-674563 is a potent, orally available Akt1 inhibitor with an IC(50) of 11nM. It also displays activity against PKA and CDK2 with IC(50) values of 16 and 46nM respectively.
Supplier:
Adipogen
Description:
KU0063794 is a highly specific inhibitor of the mammalian target of rapamycin (mTOR). It inhibits both mTORC1 and mTORC2 with an IC(50) of approximately 10nM.
Catalog Number:
(80054-800)
Supplier:
MilliporeSigma
Description:
A potent and reversible inhibitor of histone deacetylase
Supplier:
Adipogen
Description:
Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and DYRK1A inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
Supplier:
Adipogen
Description:
R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
Supplier:
Adipogen
Description:
Cabozantinib is very potent inhibitor, with an IC(50) of less than 10nM for VEGFR2, MET, Kit and FLT3-ITD.
Supplier:
MP Biomedicals
Description:
Storage: +4 °C
D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous tumors than in normal tissues. It is inactivated by binding to avidin. D-Biotin may be used to elute proteins from avidin/streptavidin resins. It is widely used for dietary supplements and fortified foods. It is also used for tablets and hard-shell capsule preparation due to its pharmaceutical properties. Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide. Soluble in water (22 mg/100 mL), ethanol (80 mg/100 mL), more soluble in hot water and in dilute alkalies; insoluble in other common organic solvents. Soluble in 2 M Ammonium hydroxide (50 mg/mL - clear, colorless solution), dimethylformamide (1.7 mg/mL).
Supplier:
TCI America
Description:
CAS Number: 111-21-7
MDL Number: MFCD00026213 Molecular Formula: C10H18O6 Molecular Weight: 234.25 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 300 Flash Point (°C): 174 Specific Gravity (20/20): 1.12
Catalog Number:
(IC10045980)
Supplier:
Adipogen
Description:
Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo. Antifungal. Potent and effective inhibitor of formyl peptide receptor (FPR) and formyl peptide-induced superoxide formation. Shows no immunosuppresive activity like other cyclosporins.
Supplier:
Adipogen
Description:
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.
Supplier:
Adipogen
Description:
SB202190 is potent and selective inhibitor of the p38alpha and beta, with IC(50) values of 50 and 100nM respectively. It is a powerful regulator of LPS-induced mRNAs in monocytes.
Supplier:
Adipogen
Description:
GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).
Supplier:
Thermo Scientific Chemicals
Description:
Standard for rating diesel-fuel ignition qualities
Supplier:
Adipogen
Description:
SB-216763 is a potent and selective ATP-competitive GSK-3 inhibitor with an IC(50) of 34.3nM for GSK-3alpha, and similar activity for GSK-3beta.
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