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Supplier:
ALADDIN SCIENTIFIC
Description:
5-Amino-4-bromo-3-methyl-1-phenyl-1H-pyrazole ≥96%
Supplier:
BeanTown Chemical
Description:
CAS: 65501-24-8; EC No: 241-543-5; MDL No: MFCD00149672; RTECS: MC0372000
Crystalline/Powder; Molecular Formula: C10H13K3N2O8·2H2O; MW: 442.55
Melting Point: 182° (decomposes)
Catalog Number:
(103011-366)
Supplier:
Anaspec Inc
Description:
Widely used for measuring membrane potential of mitochondria; 585/520 Fluorescence ratio increases upon cell hyper-polarization.
Catalog Number:
(IC10262383)
Supplier:
MP Biomedicals
Description:
L-Phenylalanine is one of the 20 amino acids. It is an essential amino acid. It contains an aromatic side chain, which contributes to ultraviolet absorbance and fluorescence properties.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
(Ethylenedinitrilo)Tetraacetic Acid, Disodium Salt, Dihydrate powder.
Catalog Number:
(EM1.08445.0250)
Supplier:
AAT BIOQUEST INC
Description:
JC-1 is widely used for determining mitochondrial membrane potential with flow cytometry.
Supplier:
Adipogen
Description:
CI-1040 (PD184352) is an orally active, highly specific, small-molecule inhibitor of MEK1/2, which is a key component of the ERK/MAPK pathway. It has an IC(50) of 17nM.
Supplier:
Adipogen
Description:
Truncated analog of alpha-GalCer. iNKT cell glycolipid agonist. Immunosuppressive. Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in release of a mixture of Th1 and Th2 cytokines. Induces stronger interleukin-4 (IL-4) secretion and weaker interferon-gamma (IFN-gamma) secretion than alpha-GalCer both in vitro and in vivo. Inducer of interleukin-10 (IL-10) and suppressor of diabetes. Shown to prevent experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of multiple sclerosis. Has beneficial effects on type I diabetes in NOD mice. Suppressor of collagen-induced arthritis. Might be useful for immunotherapy of transplant rejection.
Catalog Number:
(JT5632-2)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Standardization at 25 °C traceable to NIST Standard Reference Material.
Supplier:
MP Biomedicals
Description:
Muscimol is a structural analog of γ-amino butyric acid. It functions as a GABA-agonist: a positive analog of the natural transmitter, which can activate GABA receptors in the brain. Muscimol is an isoxazole derivative occurring naturally in the mushroom Amanita muscaria.
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Supplier:
TCI America
Description:
CAS Number: 111-42-2
MDL Number: MFCD00002843 Molecular Formula: C4H11NO2 Molecular Weight: 105.14 Purity/Analysis Method: >99.0% (GC,T) Form: Crystal Boiling point (°C): 269 Flash Point (°C): 160 Freezing point (°C): 27
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
EDTA disodium salt dihydrate 99.0-101.0% (dried basis), crystals USP, Multi-Compendial
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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