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(6-(Trifluoromethyl)-1H-indazol-4-yl)boronic+acid


51,394  results were found

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Supplier:  Sino Biological
Description:   A DNA sequence encoding the C-terminal segment of human IL33 (NP_254274.1) (Ser 112-Thr 270) was expressed with an initial Met at the N-terminus.
Supplier:  AMBEED, INC
Description:   D-Leucine methyl ester hydrochloride, Purity: 98%, CAS Number: 5845-53-4, Appearance: Form: Crystal - Powder, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100g

Supplier:  Sino Biological
Description:   This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SerpinD1 (rM SerpinD1; Catalog#50121-M08H; NP_032249.3; Met 1-Ser 478).

Supplier:  Sino Biological
Description:   This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD2 (rM CD2; Catalog#50537-M08H; NP_038514.1; Met 1-Ser 203).
Supplier:  Thermo Scientific Chemicals
Description:   100G
MSDS SDS
Supplier:  ACROBIOSYSTEMS INC MS
Description:   Cynomolgus TREM2 Protein, His Tag, Source: expressed from human 293 cells (HEK293). It contains AA His 19 - Ser 174, Predicted N-terminus: His 19, protein carries a polyhistidine tag at the C-terminus, Synonyms: Triggering receptor, Source: expressed on myeloid cells 2/TREM2/TREM-2, Size: 100uG
Supplier:  ACROBIOSYSTEMS INC MS
Description:   SARS-CoV-2 S2 protein, His Tag, Source: expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at C-terminus, Predicted N-terminus: Ser 686, Synonyms: Spike, S2 protein, Spike glycoprotein Subunit2, S glycoprotein Subunit2, Spike protein S2, Size: 100uG
Supplier:  ACROBIOSYSTEMS INC MS
Description:   SARS S protein (R667A, K968P, V969P), His Tag (MALS verified), Source: expressed with T4 fibritin trimerization motif, polyhistidine tag at the C-terminus, Predicted N-terminus: Ser 14, protein carries polyhistidine tag at C-terminus, Synonyms: Spike, Spike glycoprotein, S glycoprotein, Size: 100uG
Catalog Number: (100505-382)

Supplier:  R&D Systems
Description:   Potentiator, acts glycine site
Supplier:  TCI America
Description:   CAS Number: 302-84-1
MDL Number: MFCD00064223
Molecular Formula: C3H7NO3
Molecular Weight: 105.09
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Color: White
Melting point (°C): 240
MSDS SDS
Supplier:  ACROBIOSYSTEMS INC MS
Description:   Mouse Nectin-4 Protein, His Tag, low endotoxin, Source: expressed from human 293 cells (HEK293). It contains AA Gly 31 - Ser 347, Predicted N-terminus: Gly 31, protein carries a polyhistidine tag at the C-terminus, Synonyms: NECTIN4, LNIR,  PRR4,  PVRL4, Size: 100uG

Supplier:  Bioss
Description:   Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.

Supplier:  Bioss
Description:   Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.
Supplier:  Bioss
Description:   Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.
Supplier:  ACROBIOSYSTEMS INC MS
Description:   Human IL-2 R beta & IL-2 R alpha & IL-2 R gamma Protein FcAvitag & FcAvitag MALS verified, Biotinylated, Source: expressed from human 293 cells HEK293. It contains AA Ala 27 - Asp 239 & Glu 22 - Ser 212 & Leu 23 - Asn 254, Size: 200uG
Supplier:  ACROBIOSYSTEMS INC MS
Description:   Human latent GDF-8 Protein, His Tag, Source: expressed from HEK293. It contains AA Asn 24 - Ser 375, Predicted N-terminus: His, protein carries a polyhistidine tag at the N-terminus, Synonyms: latent GDF-8, GDF-8, Myostatin, GDF8, MSTN, Growth/differentiation factor 8, Size: 500uG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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