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4,6-Dimethoxy-5-nitropyrimidine
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4,6-Dimethoxy-5-nitropyrimidine
Catalog Number:
(77897-375)
Supplier:
AOB CHEM USA
Description:
3-BROMO-44-DIMETHOXY-11-BIPHENYL 500MG
Catalog Number:
(77883-601)
Supplier:
AMBEED, INC
Description:
710-DIMETHOXY-10-DAB III 100MG
Catalog Number:
(77906-417)
Supplier:
AOB CHEM USA
Description:
ETHYL 25-DIMETHOXY-4-METHYL-Α-OXOB 500MG
Catalog Number:
(76485-826)
Supplier:
AAT BIOQUEST INC
Description:
Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. Fluorophore-tagged drugs, such as gentamicin-Texas Red (GTTR) conjugates, have been used to identify drug trafficking routes across the BLB and into hair cells, and specifically in the cochlea - the sensory organ responsible for hearing. Identifying the mechanisms involved in the intracochlear trafficking of ototoxic drugs to hair cells is of fundamental as well as clinical importance. Texas Red-gentamicin conjugate (GTTR) provides researchers a valuable tool to study the cellular uptake, kinetics and distribution of gentamicin through fluorescence techniques, such as fluorescence microscopy, fluorescence correlation spectroscopy, single molecule spectroscopy. The TR fluorophore can be conveniently excited from 500-600 nm, with an emission maximum centered around 610 nm. Acute nephrotoxicity and permanent ototoxicity are serious side-effects that increase patient morbidity, or induce permanent auditory and vestibular deficits. Several approaches have been used to study the intracellular mechanisms induced by ototoxic drugs. However, ototoxic drugs must first cross the blood-labyrinth barrier (BLB) before entering sensory hair cells to exert their cytotoxic effect that leads to hearing loss and deafness. The BLB is similar to the blood-brain barrier (BBB), and is composed of tight junction-coupled endothelial and epithelial barrier layers that transport nutrients and ions from one side of the barrier to the other.
Catalog Number:
(101830-744)
Supplier:
Matrix Scientific
Description:
1-(2-AMINOETHYL)-4,6-DIMETHYL
Catalog Number:
(77893-295)
Supplier:
AMBEED, INC
Description:
46-DICHLOROPICOLINONITRILE 5G
Catalog Number:
(77875-250)
Supplier:
AMBEED, INC
Description:
46-DIAMINOPYRIMIDINE 25G
Catalog Number:
(102628-116)
Supplier:
Chem Impex International
Description:
4,6-DIHYDROXYPYRIMIDINE 25G
Catalog Number:
(102582-478)
Supplier:
Chem Impex International
Description:
4,6-DICHLOROPYRIMIDINE 1KG
Catalog Number:
(102560-868)
Supplier:
Chem Impex International
Description:
4,6-DIHYDROXYPYRIMIDINE 250G
Catalog Number:
(102564-038)
Supplier:
Chem Impex International
Description:
4,6-DIMETHOXYSALICYLALDE 5G
Catalog Number:
(102633-880)
Supplier:
Chem Impex International
Description:
2-AMINO-4,6-DICHLOROPYRI 5G
Catalog Number:
(102564-336)
Supplier:
Chem Impex International
Description:
4,6-DICHLORO-5-NITROPYRI 100G
Catalog Number:
(102631-196)
Supplier:
Chem Impex International
Description:
2-METHYLTHIO-4,6-DICHLOR 100G
Catalog Number:
(77902-931)
Supplier:
AMBEED, INC
Description:
A462182 89336-46-9 5G
Catalog Number:
(ALA413612-25MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
APD668 832714-46-2 25MG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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