Carl Roth GmbH
Supplier:
Adipogen
Description:
The compound (Akt-I-2) inhibited both Akt1 and Akt2 with IC(50) values of 2.7 and 21 µM respectively. It does not inhibit AKT3. The compound is a reversible inhibitor, and exhibits a linear mixed-type inhibition against ATP and peptide substrate. In addition to inhibiting kinase activity of AKT1 and AKT2 isoforms, AKT-I-1,2 blocked the phosphorylation and activation of AKT1 and AKT2 by PDK1 (phosphoinositide-dependent kinase 1). The inhibitor was found to be cell-active and to block phosphorylation of Akt at Thr308 and Ser473, reduce the levels of active Akt in cells, block the phosphorylation of known Akt substrates and promote TRAIL (tumour-necrosis-factor-related apoptosis-inducing ligand)-induced apoptosis in LNCap prostate cancer cells.
Supplier:
AMBEED, INC
Description:
H-Lys(Z)-OMe.HCl, Purity: 98%, CAS number: 27894-50-4, Appearance: Form: powder Colour: white, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 100G
Catalog Number:
(101943-390)
Supplier:
Matrix Scientific
Description:
MF=C13H12Cln3O2S MW=309.78 Cas=137118-00-4 1G
Catalog Number:
(101817-488)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024138-500MG , MDL Number: MFCD03930931
Supplier:
Matrix Scientific
Description:
MF=C7H8Clf3N2 MW=212.60 Cas=3107-34-4 MDL=MFCD00102619 ,25G
Catalog Number:
(77692-548)
Supplier:
LGC STANDARDS
Description:
4-Methylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one Hydrochloride (4-Methylaminophenazone Hydrochloride), Mikromol, LGC Standards
Catalog Number:
(101934-732)
Supplier:
Matrix Scientific
Description:
MF=C11H14Cln3Os MW=271.77 ,250Mg
Catalog Number:
(101934-502)
Supplier:
Matrix Scientific
Description:
MF=C17H27Cln2 MW=294.87 ,250Mg
Supplier:
AMBEED, INC
Description:
2,5-Dichlorophenylhydrazinium chloride 98%
Catalog Number:
(77988-235)
Supplier:
LGC STANDARDS
Description:
L-Lysine-13C6,15N2 Hydrochloride, TRC, LGC Standards
Catalog Number:
(101882-310)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 047993-500MG , MDL Number: MFCD11553074
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052910-500MG , MDL Number: MFCD13562446
Supplier:
LGC STANDARDS
Description:
Nisin Z (~80%) Hydrochloride, TRC, LGC Standards
Catalog Number:
(77991-286)
Supplier:
LGC STANDARDS
Description:
ent-Paroxetine Hydrochloride, TRC, LGC Standards
Supplier:
LGC STANDARDS
Description:
4-epi-Tetracycline Hydrochloride, TRC, LGC Standards
Catalog Number:
(77988-378)
Supplier:
LGC STANDARDS
Description:
Medetomidine-d3 Hydrochloride, TRC, LGC Standards
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