4-Bromo-4\',4\'\'-dimethoxytriphenylamine
Supplier:
Adipogen
Description:
Cell-permeable non-fluorescent reactive oxygen species (ROS) indicator. Passively diffuses across membranes where it is oxidized by peroxynitrite to rhodamine 123 which localizes in the mitochondria and exhibits green fluorescence (Ex/Em wavelengths of 500 and 536 nm). Used to investigate reactive oxygen intermediates produced by human and murine phagocytes, activated rat mast cells and cultured endothelial cells. In addition, it has been used together with Fura Red calcium indicator to simultaneously measure oxidative bursts and Ca2+ fluxes in monocytes and granulocytes. Dihydrorhodamine 123 has been shown to be a more sensitive probe than H2DCFDA for detecting granulocyte respiratory bursts.
Supplier:
Invitrogen
Description:
Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).
Supplier:
AMBEED, INC
Description:
1-(1H-Benzo[d]imidazol-2-yl)-N-methylmethanamine, Purity: 98%, CAS Number: 98997-01-4, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 250mg
Catalog Number:
(AAJ63784-EXG)
Supplier:
Thermo Scientific Chemicals
Description:
This leptomycin B is a potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus.
Catalog Number:
(80017-392)
Catalog Number:
(89139-198)
Supplier:
Biotium
Description:
Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00077263
Notes: Transition interval: pH 6.0 (yellow) to pH 7.6 (blue)
Supplier:
Adipogen
Description:
Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase.
Supplier:
Spectrum Chemicals
Description:
Thiamine Hydrochloride, FCC is the hydrochloride salt of vitamin B1 and used to treat or prevent vitamin B1 deficiency. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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Supplier:
Chem Impex International
Description:
ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na<sub>2</sub>, oxidized form)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na<sub>2</sub>, oxidized form)
Supplier:
TCI America
Description:
CAS Number: 1192-62-7
MDL Number: MFCD00003242 Molecular Formula: C6H6O2 Molecular Weight: 110.11 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 173 Flash Point (°C): 71 Freezing point (°C): 28
Catalog Number:
(89152-694)
Supplier:
Enzo Life Sciences
Description:
M2 receptor modulator.
Supplier:
Biotium
Description:
Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Fluo-3 AM ester itself does not bind Ca2 , but it is readily hydrolyzed to Fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening.
Catalog Number:
(101875-982)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046542-500MG , MDL Number: MFCD09817427
Supplier:
Enzo Life Sciences
Description:
Potent and orally active Lck/Src inhibitor.
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