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4-(4-Chlorophenyl)butyric+acid
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4-(4-Chlorophenyl)butyric+acid
Catalog Number:
(102542-636)
Supplier:
Matrix Scientific
Description:
MF=C9H8BRCLO2 MW=263.52 CAS=85259-19-4 MDL=MFCD08444353 5G
Supplier:
AMBEED, INC
Description:
2-Amino-3-(2-chlorophenyl)propanoic acid, Purity: 95%, CAS Number: 14091-11-3, Appearance: White to off-white solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100g
Supplier:
AMBEED, INC
Description:
CX-4945 98%
Catalog Number:
(77746-231)
Supplier:
AMBEED, INC
Description:
PS-48 ≥98%
Supplier:
Thermo Scientific Chemicals
Description:
Antiseptic and disinfectant agent
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042568-500MG , MDL Number: MFCD00172807
Catalog Number:
(76909-696)
Supplier:
AOB CHEM USA
Description:
3-Bromo-5-chlorophenylboronic acid ≥97%
Catalog Number:
(10430-698)
Supplier:
Bioss
Description:
Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
Catalog Number:
(TCC0975-025G)
Supplier:
TCI America
Description:
CAS Number: 1866-38-2
MDL Number: MFCD00004384 Molecular Formula: C9H7ClO2 Molecular Weight: 182.60 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 164
Catalog Number:
(10300-200)
Supplier:
Bioss
Description:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
Catalog Number:
(10300-196)
Supplier:
Bioss
Description:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
Catalog Number:
(76906-374)
Supplier:
AOB CHEM USA
Description:
4-Benzyloxy-3-chlorophenylboronic acid ≥97%
Catalog Number:
(77692-469)
Supplier:
LGC STANDARDS
Description:
2-[2-[(2-Bromo-6-chlorophenyl)amino]phenyl]acetic Acid, Mikromol, LGC Standards
Supplier:
AOB CHEM USA
Description:
4-Benzylcarbamoyl-3-chlorophenylboronic acid ≥97%
Supplier:
TCI America
Description:
4-Benzyloxy-3-chlorophenylboronic Acid (contains varying amounts of Anhydride), CAS Number: 845551-44-2, Molecular Formula: C13H12BClO3, Synonyms: 4-Benzyloxy-3-chlorobenzeneboronic Acid (contains varying amounts of Anhydride), Size: 5G
Supplier:
Thermo Scientific Chemicals
Description:
An L-type calcium channel antagonist with potent antioxidant activity
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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