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Supplier:  AMBEED, INC
Description:   1,1'-Diethyl-[4,4'-bipyridine]-1,1'-diium bromide, Purity: 97%, CAS Number: 53721-12-3, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 5g
Supplier:  TLC PHARMACEUTICAL STANDARD LTD
Description:   Pharmaceutical Standards, Umeclidinium Bromide Impurity 11 Bromide
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 034775-1G , MDL Number: MFCD11845799
Supplier:  TLC PHARMACEUTICAL STANDARD LTD
Description:   Pharmaceutical Standards, Olmesartan Medoxomil Impurity 11
Supplier:  AMBEED, INC
Description:   1,1'-(Methylenebis(2-ethyl-6-methyl-4,1-phenylene))bis(1H-pyrrole-2,5-dione) 98%
Supplier:  AMBEED, INC
Description:   (R)-3,3'-Bis3,5-bis(trifluoromethyl)phenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthol, Purity: 98%, CAS Number: 618854-91-4, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Supplier:  AMBEED, INC
Description:   Ruthenium(2+), tris(2,2'-bipyrimidine-KN1,KN1')-, (OC-6-11)-, hexafluorophosphate(1-) (1:2), Purity: 97%, CAS Number: 85335-55-3, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 1G
Supplier:  PeproTech, Inc.
Description:   Produced from sera of rabbits immunized with highly pure Recombinant Human IL-11. Anti­Human IL-11­specific antibody was purified by affinity chromatography employing an immobilized Human IL-11 matrix.

Supplier:  Adipogen
Description:   Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.

Supplier:  Adipogen
Description:   Inflammatory caspases (also known as group I caspases) are encoded by three main genes in humans, caspase-1, caspase-4 and caspase-5 and three main genes in mouse, caspase-1, caspase-11 and caspase-12. Caspase-11 is the murine orthologue of human caspase-4 and -5. Murine caspase-11 is a poorly characterized member of the caspase-1 subfamily. Caspase-11-deficient embryonic fibroblasts are resistant to apoptosis induced by ectopic expression of caspase-1, suggesting that caspase-11 is an upstream activator of caspase-1. Unlike caspase-1, the expression of caspase-11 is LPS-inducible and it is reasonable to postulate that other members of the family are regulated at the transcriptional or translational level by extracellular stimuli. Recently caspase-11 has been shown to be required for activation of the Nlrp3 inflammasome upon E. coli, V. cholerae and C. rodentium infection. The upstream activators of caspase-11 are TLR4 and TRIF, that modulate enteropathogen-induced inflammasome activation by promoting caspase-11 expression and activation. Formation of ASC foci (specks), a measure of NLRP3/ASC complex formation, requires caspase-11 but not caspase-1 indicating that caspase-11 acts upstream of the NLRP3/ASC complex.
Catalog Number: (75835-340)

Supplier:  Restek
Description:   11 components
Supplier:  Matrix Scientific
Description:   MF=C13H14N2O3S MW=278.33 MDL=MFCD18070632 ,500Mg
Supplier:  AMBEED, INC
Description:   (S)-3,3'-Bis(4-(trifluoromethyl)phenyl)-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol, Purity: 98%, CAS Number: 1228600-98-3, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 100MG
Supplier:  AMBEED, INC
Description:   (4S,4'S)-2,2'-(Cycloheptane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole), Purity: 97%, CAS Number: 2828432-05-7, Appearance: Solid or liquid, Storage: Inert atmosphere, 2-8C, Size: 100MG

Supplier:  Prosci
Description:   Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
Supplier:  Strem Chemicals Inc
Description:   BINAP
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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