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4-Bromo-5-(trifluoromethyl)-1H-indazole
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4-Bromo-5-(trifluoromethyl)-1H-indazole
Catalog Number:
(77746-332)
Supplier:
AMBEED, INC
Description:
4-Chloro-2-(trifluoromethyl)benzaldehyde ≥98%
Catalog Number:
(101783-956)
Supplier:
Matrix Scientific
Description:
MF=C14H10Clf3O3 MW=318.68 Cas=175276-59-2 MDL=MFCD00275556 ,1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046665-500MG , MDL Number: MFCD12025892
Catalog Number:
(102898-026)
Supplier:
Matrix Scientific
Description:
MF=C12H9F3N2O2 MW=270.21 1G
Catalog Number:
(76987-520)
Supplier:
AMBEED, INC
Description:
3-Chloro-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, Purity: 95%, CAS number: 923849-73-4, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Catalog Number:
(101851-050)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041251-1G , MDL Number: MFCD10697912
Catalog Number:
(102838-542)
Supplier:
Matrix Scientific
Description:
2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid ≥95%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052763-500MG , MDL Number: MFCD11119991
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052723-500MG , MDL Number: MFCD11122453
Catalog Number:
(77671-406)
Supplier:
AMBEED, INC
Description:
3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine ≥98%
Catalog Number:
(10300-338)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Supplier:
AMBEED, INC
Description:
4-(Trifluoromethyl)pyrimidine-5-carboxylic acid, Purity: 95%, CAS Number: 220880-12-6, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Catalog Number:
(76671-354)
Supplier:
AMBEED, INC
Description:
2-(3-(Trifluoromethyl)phenyl)piperidine hydrochloride, Purity: 95%, CAS Number: 1184989-97-6, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1G
Catalog Number:
(101802-910)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 012581-1G , MDL Number: MFCD11100463
Catalog Number:
(77198-684)
Supplier:
AMBEED, INC
Description:
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)aniline, Purity: 97%, CAS Number: 1259285-61-4, Appearance: Pale-yellow to Yellow-brown Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 1g
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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