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4-Butylcyclohexanecarboxylic+acid+(cis+and+trans+mixture)
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4-Butylcyclohexanecarboxylic+acid+(cis+and+trans+mixture)
Supplier:
VWR International
Description:
Application specific highly polar phase, ideal for detailed cis/trans FAMEs separation.
Catalog Number:
(76012-302)
Supplier:
Prosci
Description:
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium.
Catalog Number:
(101189-698)
Supplier:
BioVendor
Description:
Cyclophilins belong to a group of proteins that have peptidyl-prolyl cis-trans isomerase activity; such proteins are collectively known as immunophilins and also include the FK-506-binding proteins and the parvulins. Cyclophilins are found in all cells of all organisms studied, in both prokaryotes and eukaryotes. Human have a total of 16 cyclophilin proteins. Cyclophilins also have varying degrees of affinity for the immunosuppressive drug Cyclosporine A (CsA), a cyclic 11-amino-acid peptide produced by fungus Tolypocladium infantum. Cyclophilin A, in particular, is the major intracellular receptor for CsA. Cyclophilin A (CYPA) is the first member of the cyclophilins to be identified in mammals. Human genes of CYPA, also known as Cyp18, are located on chromosome 7p11.2-p13 and encode the protein, which consists of 165 amino acid residues with a relative molecular mass approximately 18 kDa. Human CYPA has an eight-stranded antiparallel β-barrel structure, with two α-helices enclosing the barrel from either side. Seven aromatic and other hydrophobic residues form a compact hydrophobic core within the barrel, usually in the area where CsA binds. A loop from Lys118 ti His126 and four β-strands (β3-β6) make up the binding site for CsA. In mammals, the CsA-CYPA complex binds to and inhibits calcineurin, a calcium-calmodulin-activated serine/threonine-specific protein phosphatase. The inhibition of calcineurin blocks the translocation of nuclear factor of activated T cells from the cytosol to the nucleus, thus preventing the transcription of genes encoding cytokines such as interleukin-2.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl-5-norbornene-2,3-dicarboxylic anhydride (mixture of isomers) 95%
Supplier:
AMBEED, INC
Description:
Farnesol (mixture of isomers) 95% (mixture of isomers)
Catalog Number:
(77439-712)
Supplier:
Bioss
Description:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing MLL5. Mediates retinoic acid-induced granulopoiesis.
Supplier:
Thermo Scientific Chemicals
Description:
trans-2-cis-6-Nonadien-1-al 97%. 5g.
Catalog Number:
(10234-004)
Supplier:
Bioss
Description:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Supplier:
CHI Scientific
Description:
Kit Primacell 2* Mouse Esophagus FibrOut*, Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes.
Supplier:
CHI Scientific
Description:
Kit PrimaCell*2 Mouse Kidney FIBROUT*2: Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Farnesol (mixture of isomers) 96%
Supplier:
TCI America
Description:
CAS Number: 29118-70-5
MDL Number: MFCD00021191 Molecular Formula: C12H20O2 Molecular Weight: 196.29 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 159
Supplier:
AMBEED, INC
Description:
Trans,cis-2,6-nonadien-1-ol, Purity: 98%, CAS Number: 28069-72-9, Appearance: Colorless to light yellow liquid, Storage: Inert atmosphere, Room Temperature, Size: 1G
Supplier:
CHI Scientific
Description:
Kit PrimaCell* 2 Rat Heart FibrOut* 2, Fibroblast Inhibitory System (for 500 ml medium), mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes, stable at 4-8 degreeC, effective up to 4
Supplier:
TCI America
Description:
CAS Number: 4602-84-0
MDL Number: MFCD00002918 Molecular Formula: C15H26O Molecular Weight: 222.37 Form: Clear Liquid Color: Colorless Boiling point (°C): 143 Flash Point (°C): 96 Specific Gravity (20/20): 0.89
Catalog Number:
(10786-906)
Supplier:
CHI Scientific
Description:
Kit PrimaCell* Human Bone Marrow FibrOut*, Fibroblast Inhibitory System (for 500 ml medium), mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes, stable at 4-8 degreeC, effective up to 4
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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