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4-Ethynyl-1,1\\\\\\\\\\\\\\\'-biphenyl
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4-Ethynyl-1,1\\\\\\\\\\\\\\\'-biphenyl
Supplier:
BeanTown Chemical
Description:
CAS: 152670-41-2; MDL No: MFCD09261380
Solid; Molecular Formula: C32H24N2; MW: 436.56
Melting Point: 252-258°
Refractive Index: 1.229
Supplier:
Thermo Scientific Chemicals
Description:
10g CAS: 20443-74-7, MDL: MFCD01631918
Catalog Number:
(102541-718)
Supplier:
Matrix Scientific
Description:
MF=C12H10O2 MW=186.21 CAS=92-88-6 MDL=MFCD00002348 100G
Supplier:
AMBEED, INC
Description:
o-Terphenyl 98%
Supplier:
TCI America
Description:
CAS Number: 2143-90-0
MDL Number: MFCD00143334 Molecular Formula: C13H11NO3 Molecular Weight: 229.24 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 110
Supplier:
AMBEED, INC
Description:
4,4'-Biphenyldicarboxaldehyde 95%
Catalog Number:
(103011-118)
Supplier:
Anaspec Inc
Description:
Congo Red, UltraPure Grade, Early diagnosis and classification of amyloid deposition, Molecular Weight: 696.7, Spectral Properties: Abs/Em = 497/NA nm, Solvent System: Water, CAS number: 573-58-0, Molecular formula: C32H22N6Na2O6S2, Physical State: Solid, Storage: -20 deg C, Size: 1 g
Supplier:
APOLLO SCIENTIFIC
Description:
4-Bromo-2-fluorobiphenyl 97%
Catalog Number:
(TCE0568-25G)
Supplier:
TCI America
Description:
CAS Number: 5668-93-9
MDL Number: MFCD00796638 Molecular Formula: C14H14 Molecular Weight: 182.27 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 284 Melting point (°C): -27 Specific Gravity (20/20): 1.00
Supplier:
AMBEED, INC
Description:
2-Methoxybiphenyl, Purity: 98%, CAS Number: 86-26-0, Appearance: Colorless or Off white to Yellow Solid or liquid, Storage: Sealed in dry, Room Temperature, Size: 100g
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2-Bromobiphenyl (PBB No. 1) 98%
Catalog Number:
(101789-372)
Supplier:
Matrix Scientific
Description:
MF=C12H11N MW=169.23 Cas=2243-47-2 MDL=MFCD00047846 5G
Supplier:
AMBEED, INC
Description:
4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid, Purity: 98%, CAS number: 144701-48-4, Appearance: Form: Crystal - Powder / Colour: White - Almost white, Storage: Sealed in dry, Room Temperature, Size: 25G
Catalog Number:
(101858-018)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042881-1G , MDL Number: MFCD08276944
Catalog Number:
(101779-118)
Supplier:
ALADDIN SCIENTIFIC
Description:
Product DescriptionDGAT-1 inhibitor A 922500 (A-922500) reduces serum triglyceride levels from baseline at all doses tested; however, this is only statistically significant at the 3 mg/kg dose, which lowers serum triglycerides by 53%. Similarly, the 3 mg/kg dose of A 922500 significantly reduces serum FFA concentrations by 55% and total cholesterol by 25%. DGAT-1 inhibition has no significant effect on body weight at any dose tested. Although A 922500 dpes not significantly affect LDL-cholesterol or HDL-cholesterol individually, the serum LDL/HDL-cholesterol ratio is significantly improved by A 922500 at 0.3 and 3 mg/kg. Similar to the dyslipidemic hamster, treatment with 3 mg/kg A 922500 significantly reduces serum triglyceride concentrations (39%). FFA levels significantly increase over the 14-day period in vehicle-treated animals. This increase is inhibited in a dose-dependent manner by A 922500 such that FFA concentrations are 32% lower after 14 days of treatment with the DGAT-1 inhibitor at 3 mg/kg, compared with the vehicle group (p < 0.05). HDL-cholesterol is significantly increased from baseline levels by A 922500 at 0.3 and 3 mg/kg; however, this is only significantly increased compared with vehicle at the 3 mg/kg dose. Body weight significantly increases over the 2-week period in vehicle-treated rats, and this is not affected by A 922500. LDL-cholesterol is significantly reduced in the vehicle treated group. DGAT-1 inhibition does not further reduce LDL-cholesterol and has no effect on total cholesterol.Product ApplicationA922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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