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(2-(Difluoromethoxy)pyridin-4-yl)boronic+acid
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(2-(Difluoromethoxy)pyridin-4-yl)boronic+acid
Catalog Number:
(10268-762)
Supplier:
Bioss
Description:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
Catalog Number:
(10081-950)
Supplier:
Proteintech
Description:
ATP1A2 (Na+/K+-ATPase α-2 subunit) is the catalytic component of the active enzyme Na+/K+-ATPase, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. The Na+/K+-ATPase is composed of a larger catalytic α-subunit (~110 kDa) and a small β-subunit (~55 kDa). The α subunit has four isoforms identified to date: α1, α2, α3 and α4.The α1 isoform is expressed ubiquitously but the α2 isoform is present largely in the skeletal muscle, heart and vascular smooth muscle. The α3 isoform is found almost exclusively in neurons and ovaries. The α4 isoform is expressed in sperm. This antibody was raised against the internal region of the human ATP1A2 and can recognizes all the isoforms of α subunit. The 65kDa band detected occasionally may be the degradation product of ATP1A2.
Catalog Number:
(RL812-1902)
Supplier:
Rockland Immunochemical
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.
Catalog Number:
(89293-282)
Supplier:
Genetex
Description:
Goat polyclonal antibody to SLC12A2
Catalog Number:
(77146-802)
Supplier:
AMBEED, INC
Description:
tert-Butyl 2-(tert-butyl)hydrazinecarboxylate, Purity: 98%, CAS Number: 60295-52-5, Appearance: White to Yellow Solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 5g
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4-tert-Butylpyrocatechol 99%
Catalog Number:
(76098-522)
Supplier:
Bioss
Description:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Supplier:
AMBEED, INC
Description:
L-tert-Leucinol 98%
Supplier:
AMBEED, INC
Description:
4-tert-Butyl-o-phenylenediamine 97%
Catalog Number:
(EM-SX0607N-6)
Supplier:
AMBEED, INC
Description:
4-tert-Butyl-N-(tert-butoxycarbonyl)-L-aspartate 97%
Supplier:
AMBEED, INC
Description:
4-tert-Butylpyridine 98%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4-tert-Butylcyclohexanone 99%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4'-tert-Butylacetophenone 98%
Supplier:
AMBEED, INC
Description:
2-tert-Butylaniline 98%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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