5-Amino-2-methyl-2H-tetrazole
Supplier:
APOLLO SCIENTIFIC
Description:
1H,1H,2H-Perfluoro-1-hexene 98%
Catalog Number:
(101919-846)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060324-500MG , MDL Number: MFCD13857451
Catalog Number:
(101907-100)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054334-500MG , MDL Number: MFCD14581677
Supplier:
AMBEED, INC
Description:
4-(Hydroxymethyl)tetrahydro-2H-pyran-4-carbonitrile, Purity: 98%, CAS Number: 1010836-56-2, Appearance: Liquid or Solid or Semi-solid or lump, Storage: Sealed in dry, 2-8 deg C, Size: 100mg
Catalog Number:
(76009-372)
Supplier:
Prosci
Description:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD) (1). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA (2). MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases (3). In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract (4).
Supplier:
AMBEED, INC
Description:
1H-Pyrrolo[3,4-c]pyridin-3(2H)-one 97%
Catalog Number:
(102834-482)
Supplier:
Matrix Scientific
Description:
2-(Tetrahydro-2H-pyran-2-ylmethoxy)pyridin-3-amine ≥97%
Catalog Number:
(102844-302)
Supplier:
Matrix Scientific
Description:
3-Nitro-2-(tetrahydro-2H-pyran-2-ylmethoxy)pyridine ≥97%
Catalog Number:
(101925-970)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063566-500MG , MDL Number: MFCD00176268
Catalog Number:
(102838-356)
Supplier:
Matrix Scientific
Description:
4,6-Dimethyl-2-oxo-2H-pyran-5-carboxylic acid ≥97%
Supplier:
TCI America
Description:
6-(Chloroacetyl)-2H-1,4-benzoxazin-3(4H)-one, CAS Number: 26518-76-3, Purity: 98.0%, Molecular Formula: C10H8ClNO3, Molecular Weight: 225.63 g/mol, Physical Form: Solid, Size: 25G
Supplier:
AMBEED, INC
Description:
7-Bromo-2H-benzo[b][1,4]thiazin-3(4H)-one, Purity: 98%, CAS number: 90814-91-8, Appearance: Form: solid, Storage: Sealed in dry, Room Temperature, Size: 5G
Catalog Number:
(102841-612)
Supplier:
Matrix Scientific
Description:
2-Acetyl-5-bromo-2H-indazole ≥97%
Catalog Number:
(101929-418)
Supplier:
Matrix Scientific
Description:
MF=C6H12N2O2 MW=144.17 Cas=59293-18-4 MDL=MFCD09752016 500Mg
Catalog Number:
(102837-834)
Supplier:
Matrix Scientific
Description:
2-Oxo-6-pentyl-2H-pyran-3-carboxylic acid ≥97%
Supplier:
AOB CHEM USA
Description:
4-(4-Ethoxy-3-fluorophenyl)tetrahydro-2H-pyran-4-ol 97
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