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Supplier:
Bachem Americas
Description:
H-Asn(Trt)-2-chlorotrityl resin (200-400 mesh) (Low Substitution) 5g, Substitution 0. 20-0. 49 mmol/g, Storage Condition: -20 +/- 5 degree C.
Catalog Number:
(H-1765.0050BA)
Supplier:
Bachem Americas
Description:
A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin (N-1000). H-1765 inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.
Supplier:
Bachem Americas
Description:
F2L is an acetylated peptide corresponding to an N-terminal fragment of the human heme-binding protein. Ac-MLGMIKNSLFGSVETWPWQVL acts specifically through the FPR-like receptor (FPRL) 2 promoting calcium mobilization and chemotaxis in dendritic cells and monocytes. In neutrophils, F2L inhibited FPR and FPRL1-mediated signaling.
Supplier:
Bachem Americas
Description:
An endogenous dipeptide with high affinity for a brain glutamate receptor. NAAG is the most abundant peptide neurotransmitter in the mammalian central nervous system.
Supplier:
Bachem Americas
Description:
Synthetic product. Potent antagonist of RANTES and macrophage inflammatory polypeptide-1α (MIP-1α). Met-RANTES inhibited RANTES- or MIP-1α-induced chemotaxis of promonocytic THP-1cells and T-cells. Although Met-RANTES antagonized RANTES and MIP-1α with similar potency in the chemotaxis response it showed a clear difference in the cytokine-induced calcium mobilization assay.
Catalog Number:
(G-1495.0001BA)
Supplier:
Bachem Americas
Description:
1G CAS: 1188-24-5 C12H25N5O3 FW: 287.36
Supplier:
Bachem Americas
Description:
Reverse sequence of Aβ 1-42 (H-1386, H-6466), inactive control for the Aβ.
Catalog Number:
(80010-258)
Catalog Number:
(G-1380.0001BA)
Supplier:
Bachem Americas
Description:
1G CAS: 3303-41-1 C6H12N2O4 FW: 176.17
Supplier:
Bachem Americas
Description:
The sequences given for angiotensin I (H-1680) and II (H-1705) correspond to the sequences of human, horse, sheep, pig, mouse, and rat angiotensins I and II.
Supplier:
Bachem Americas
Description:
Substrates for measuring the chymotryptic, PGPH, and tryptic acitivity of the 20S or 26S proteasome. See also the thrombin substrate I-1140.
Catalog Number:
(82603-978)
Supplier:
MilliporeSigma
Description:
Human, Rat Corticotropin Releasing Factor
Catalog Number:
(H-4652.0001BA)
Supplier:
Bachem Americas
Description:
LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
Supplier:
Bachem Americas
Description:
See also the pTH2 receptor agonist TIP39 (H-4878).
Supplier:
Bachem Americas
Description:
Kojro et al. observed that the PAC1 agonists PACAP-27 (H-1172) and PACAP-38 strongly increased the activity of α-secretase. Upregulation of this APP-degrading enzyme promotes the non-amyloidogenic processing of APP, i.e. reduces the production of Aβ40/42, and thus may help to prevent Alzheimer’s disease. Nasally applied PACAP-38 in APP[V717I]-transgenic mice additionally enhanced the production of the Aβ-degrading enzyme neprilysin via induction of somatostatin.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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