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3-(4-Bromophenyl)acrylaldehyde
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3-(4-Bromophenyl)acrylaldehyde
Catalog Number:
(10260-878)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Supplier:
Biotium
Description:
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(77747-575)
Supplier:
AMBEED, INC
Description:
ML-210 ≥98%
Catalog Number:
(10835-000)
Supplier:
Superior Uniform
Description:
Staff-length lab coat is made of a polyester/cotton blend white fine-line twill fabric
Supplier:
TCI America
Description:
CAS Number: 2713-33-9
MDL Number: MFCD00010315 Molecular Formula: C6H4F2O Molecular Weight: 130.09 Purity/Analysis Method: >98.0% (GC) Flash Point (°C): 57 Freezing point (°C): 35
Supplier:
Biolegend
Description:
PE anti-Histone H3 Phospho (Ser28) [HTA28]; Isotype: Rat IgG2a, κ; Reactivity: Human; Apps: ICFC; Size: 100 tests
Catalog Number:
(10852-662)
Supplier:
Sper Scientific
Description:
Fits standard test tubes 16x50 mm or larger.
Catalog Number:
(103284-468)
Supplier:
Novus Biologicals
Description:
The TRIM40 Antibody from Novus Biologicals is a rabbit polyclonal antibody to TRIM40. This antibody reacts with human. The TRIM40 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Supplier:
Dickies
Description:
Dickies® style LP812.
Supplier:
Cannon
Description:
The Cannon Four-Bulb Shear Dilution Viscometer Five Fold Dilution type measures intrinsic viscosities extrapolated to zero shear rate with negligible kinetic energy correction
Supplier:
Tonbo Biosciences
Description:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Catalog Number:
(103259-890)
Supplier:
Southern Biotechnology
Description:
In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an α chain (CD8α) and a β chain (CD8β); and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8α without CD8β. It has been suggested that CD8+β- T cells mature extrathymically, while development of the CD8α+β+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8α+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.
Catalog Number:
(10015-248)
Supplier:
OMNI INTERNATIONAL
Description:
The Omni Micro Homogenizer is a hand-held battery powered rotor-stator homogenizer designed for use inside or outside of a laboratory setting.
Supplier:
QUANTUM STORAGE SYSTEMS
Description:
Economincal small parts storage systems feature open hopper front bins with a labeling area to provide fast access to stored items.
Catalog Number:
(103321-854)
Supplier:
Novus Biologicals
Description:
The Annexin A3 Antibody (4F1) from Novus Biologicals is a mouse monoclonal antibody to Annexin A3. This antibody reacts with human. The Annexin A3 Antibody (4F1) has been validated for the following applications: Western Blot, ELISA, RNA Inhibition.
Supplier:
GE Healthcare - Whatman
Description:
These 934-AH™ RTU grade filter papers have been pre-washed, dried (or ignited), cooled, desiccated, and weighed. This eliminates the pre-treating steps that are otherwise required by the US EPA Laboratory Standard Method 2540 parts C, D, and E.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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