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Bis(2-methoxyphenyl)phosphine+oxide
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Bis(2-methoxyphenyl)phosphine+oxide
Catalog Number:
(10271-204)
Supplier:
Bioss
Description:
CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
Catalog Number:
(89158-442)
Supplier:
Enzo Life Sciences
Description:
Putative endogenous member of a growing family of lipo-amino acids (N-acyl amino acids).
Catalog Number:
(89357-958)
Supplier:
Genetex
Description:
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Catalog Number:
(BJBR673AK-4)
Supplier:
Honeywell Research Chemicals
Description:
Burdick & Jackson® BioSyn® reagents & solvents for DNA/RNA synthesis
Supplier:
HONEYWELL INTERNATIONAL INC MX
Description:
HIGH PURITY SOLVENTS, LC-MS GRADE SOLVENTS
Catalog Number:
(89151-060)
Supplier:
Enzo Life Sciences
Description:
Spin trapping reagent.
Supplier:
Adipogen
Description:
Potent peroxisome proliferator-activated receptor (PPARalpha) activator. Activates also PPARgamma but not PPARdelta. Potent anti-hypercholesterolemic agent. Hypolipidemic compound. Lipogenesis inducer. Tumor promoter. Causes increased cell proliferation and decreased apoptosis. Anti-inflammatory. Inhibits NF-kappaB transcriptional activity and decreases the inflammatory response by reducing the production of inflammatory cytokines (TNF-alpha, IL1beta). Reduces oxidative stress. Increases fatty acid oxidation. Directly affects insulin signaling. Increases glucose uptake. Reviews.
Catalog Number:
(EM8.00653.0005)
Catalog Number:
(75878-138)
Supplier:
BIOASSAY SYSTEMS
Description:
For quantitative determination of reduced and oxidized glutathione (GSH/GSSG).
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Trazodone EP Impurity A (Trazodone Hydrochloride BP Impurity A, Trazodone N1-Oxide)
Catalog Number:
(76011-476)
Supplier:
Prosci
Description:
This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described.
Supplier:
Adipogen
Description:
Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Autophagy inducer.
Catalog Number:
(77697-274)
Supplier:
LGC STANDARDS
Description:
N,N-Dimethyl-2-[5-[(methylsulfamoyl)methyl]-1H-indol-3-yl]ethanamine N-Oxide Maleate, Mikromol, LGC Standards
Catalog Number:
(10401-948)
Supplier:
Bioss
Description:
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Supplier:
Thermo Scientific Chemicals
Description:
99.99% (REO).Lump,WARNING: Irritates skin, eye, lungs; affects blood clotting,5g,25g.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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